Pravastatin (sodium)

Hersteller MedChem Express
Kategorie Produkte / Inhibitors
Typ Inhibitors
Specific against other
Clon N/A
Menge 10mM*1mL (in DMSO)
ArtNr HY-B0165A-10mM
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
CAS No.
81131-70-6
Purity
>98%
MW
4465096
Formula
C23H35NaO7
Solubility
10 mM in DMSO
Biological Description
Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 uM.
Target: HMG-CoA reductase
Pravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used in combination with diet, exercise, and weight-loss for lowering cholesterol and preventing cardiovascular disease.
Pravastatin is primarily used for the treatment of dyslipidemia and the prevention of cardiovascular disease. It is recommended to be used only after other measures such as diet, exercise, and weight reduction have not improved cholesterol levels.The evidence for the use of pravastatin is generally weaker than for other statins. The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT), failed to demonstrate a difference in all-cause mortality or nonfatal myocardial infarction/fatal coronary heart disease rates between patients receiving pravastatin 40mg daily (a common starting dose) and those receiving usual care.
Menge: 10mM*1mL (in DMSO)
Lieferbar: In stock
Listenpreis: 114,29 €
Preis: 114,29 €
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