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Oxybutynin (chloride)

Oxybutynin (chloride)

ArtNr	HY-B0267A-500mg
Hersteller	MedChem Express
CAS-Nr.	1508-65-2
Menge	500 mg
Quantity options	100 mg 10mM/1mL 500 mg
Kategorie	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer Bladder Cancer Testicular & Prostate Cancer
Typ	Inhibitors
Clon	N/A
Specific against	other
Purity	99.15
Formula	C22H32ClNO3
Citations	[1]Li H, et al. The anticholinergic drug oxybutynin inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells. Clin Exp Pharmacol Physiol. 2019 Nov;46(11):1030-1036.<br/>[2]Oki T, et al. Comparative evaluation of central muscarinic receptor binding activity by oxybutynin, tolterodine and darifenacin used to treat overactive bladder. J Urol. 2007 Feb;177(2):766-70.
Smiles	O=C(C(O)(C1=CC=CC=C1)C2CCCCC2)OCC#CCN(CC)CC.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1508-65-2
Lieferbar
Product Description	Oxybutynin chloride is an oral active and competitive mAChR antagonist with Kis of 14.3 and 5.55 nM for specific [3H]NMS binding in the mouse bladder and cerebral cortex, respectively. Oxybutynin chloride inhibits vascular Kv channels in a manner independent of anticholinergic effect, with an IC50 value of 11.51 μM. Oxybutynin chloride reduces muscle spasm in the bladder and urinary tract, can be used in study of overactive bladder syndrome (OAB)[1][2]. Oxybutynin (chloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	393.95
Clinical Information	Launched
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : ≥ 100 mg/mL\|H2O : 33.33 mg/mL (ultrasonic)
Target	mAChR; Potassium Channel
Manufacturers Target	mAChR; Potassium Channel
Manufacturers Pathway	GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Manufacturers Product type	Reference compound

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HY-B0267A-500mg-safety-datasheet.pdf