Rifampicin

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Clon N/A
Menge 10mM*1mL (in DMSO)
ArtNr HY-B0272-10mM
eClass 6.1 30220300
eClass 9.0 32160605
Lieferbar
Synonyms
Rifampin, Rifamycin AMP
CAS No.
13292-46-1
Purity
>98%
MW
8229402
Formula
C43H58N4O12
Solubility
10 mM in DMSO
Biological Description
Rifampicin is a broad-spectrum antibiotic, which inhibits the bacterial DNA-dependent RNA polymerase.
In Vitro: Rifampicin (100 mg/mL) can block the functional activity of P-glycoprotein. Rifampicin is not a substract for P-glycoprotein. The mechanism of rifampicin resistance is unassociated with the functional activity of P-glycoprotein[3].
In Vivo: Rifampicin (200, 400 mg/kg) can induce fatty liver at high concentration[1]. Rifampicin (30 mg/kg, i.p.) treatment of S464P biofilms in vivo results in a slight decline, but earlier rebinds in bioluminescence from these catheters compared with the parental signal, whereas rifampicin has no affect on bioluminescence in mice infected with mutant H481Y[2].
Menge: 10mM*1mL (in DMSO)
Lieferbar: In stock
Listenpreis: 122,86 €
Rabatt: -10,0%
Preis: 110,57 €
Sie sparen: 12,29 €
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