Amikacin (disulfate)

ArtNr	HY-B0509B-500mg
Hersteller	MedChem Express
CAS-Nr.	39831-55-5
Menge	500 mg
Quantity options	10 mM/1 mL 1 g 500 mg 5 g
Kategorie	Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Edson, R.S. and C.L. Terrell, The aminoglycosides. Mayo Clin Proc, 1999. 74(5): p. 519-28.\|[2]Ristuccia AM, et al. An overview of amikacin. Ther Drug Monit. 1985;7(1):12-25.\|[3]Siân R Kitcher, et al. ORC-13661 Protects Sensory Hair Cells From Aminoglycoside and Cisplatin Ototoxicity. JCI Insight. 2019 Aug 8;4(15):e126764. ACS Chem Biol. 2022 Jan 21;17(1):39-53. bioRxiv. 2024 May 10. Int J Antimicrob Agents. 2018 Aug;52(2):269-271. Nat Commun. 2022 Mar 2;13(1):1116. ACS Infect Dis. 2024 Apr 12;10(4):1327-1338. AMB Express. 2024 Dec 24;14(1):141. Antimicrob Agents Chemother. 2024 Oct 29:e0094524. Antimicrob Agents Chemother. 2025 May 23:e0024925. Authorea. 2025 Sep 17. bioRxiv. 2025 May 30. Commun Biol. 2025 Oct 6;8(1):1425. EBioMedicine. 2025 May 30:117:105776. Eur J Clin Microbiol Infect Dis. 2025 Jun;44(6):1493-1500. Eur J Clin Microbiol Infect Dis. 2025 Sep 29. Int J Antimicrob Agents. 2025 Jun 9:107551. Int J Med Microbiol. 2023 Mar 28;313(2):151578. J Antimicrob Chemother. 2020 Sep 1;75(9):2609-2615. J Clin Microbiol. 2025 Aug 20:e0084125. Microbiol Spectr. 2025 May 19:e0307424. Pathogens. 2025 Mar 21;14(4):302. Antibiotics (Basel). 2021 Sep 14;10(9):1110. Appl Microbiol Biotechnol. 2022 Apr;106(7):2689-2702. Curr Microbiol. 2021 Dec 14;79(1):12. J Antimicrob Chemother. 2020 Jul 1;75(7):1850-1858.
Smiles	OS(O)(=O)=O.OS(O)(=O)=O.O[C@@H]1[C@H]([C@@H](C[C@H](N)[C@H]1O[C@@]([C@@H]([C@@H](O)[C@@H]2O)O)([H])O[C@@H]2CN)NC([C@@H](O)CCN)=O)O[C@@]([C@@H]([C@@H](N)[C@@H]3O)O)([H])O[C@@H]3CO
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BAY 41-6551 (disulfate)
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Category	Reference compound / Active compounds; API
Manufacturer - Targets	Antibiotic; Bacterial
Manufacturer - HS Code	H315, H319, H335, H350, H360
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	781.76
Product Description	Amikacin disulfate (BAY 41-6551 dissulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin disulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin disulfate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin disulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria[1][2].
Manufacturer - Research Area	Infection; Cancer
Solubility	DMSO : < 1 mg/mL\|H2O : 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection
Clinical information	Launched
Isoform	Aminoglycoside
UNSPSC Code	12352005
Precautionary	H315, H319, H335, H350, H360

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