Glycyrrhizic acid

ArtNr	HY-N0184-100mg
Hersteller	MedChem Express
CAS-Nr.	1405-86-3
Menge	100 mg
Quantity options	100 g 100 mg 10mM/1mL 200 mg 25 g 500 mg 50 mg
Kategorie	Metabolism Cholesterol & Lipid Metabolism Lipoprotein Receptors & Associated Proteins Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	99.84
Formula	C42H62O16
Citations	3 Biotech. 2020 Aug;10(8):369. ACS Chem Neurosci. 2020 Mar 18;11(6):979-993. Adv Healthc Mater. 2023 Aug 21;e2301808. Adv Sci (Weinh). 2024 Aug 5:e2404408. Aging (Albany NY). 2019 Jul 7;11(13):4323-4337. Biochem Biophys Res Commun. 2021 Jan 8;540:22-28. bioRxiv. 2025 Feb 19. BMC Immunol. 2021 May 27;22(1):34. Cell Commun Signal. 2023 May 1;21(1):86. Cell Death Discov. 2024 Jan 17;10(1):34. Cell Prolif. 2020 Jun;53(6):e12829. Cell Prolif. 2024 Nov 20:e13774. Cell Signal. 2024 Jan 5:111036. Evid Based Complement Alternat Med. 2020 May 31;2020:8653783. Fish Shellfish Immunol. 2023 Nov 29:109261. Front Cell Dev Biol. 2020 Aug 11;8:713. Hepatol Commun. 2023 Dec 22;8(1):e0350. Int Immunopharmacol. 2025 Feb 18:150:114294. Int Immunopharmacol. 2025 Feb 3:149:114192. J Exp Clin Cancer Res. 2024 Apr 4;43(1):105. J Funct Foods. 2021, 104584. Mol Neurobiol. 2024 Dec 21. Pharm Biol. 2020 Dec;58(1):898-904. Pharmaceuticals. 2022, 15(2), 179. Phytomedicine. 2024 Sep 26:135:156059. Planta Med. 2021 Feb 5. Research Square Preprint. 2022 May. Research Square Preprint. 2023 Apr 27. Research Square Print. August 24th, 2022. Rev Bras Farmacogn. 2023 Jun 28. SSRN. 2025 Jan 15. World Neurosurg. 2021 Nov 24;S1878-8750(21)01796-4. bioRxiv. 2025 Feb 19. [1]Su X, et al. Glycyrrhizic acid: A promising carrier material for anticancer therapy. Biomed Pharmacother. 2017 Sep 5;95:670-678 [2]Wang LY, et al. Glycyrrhizic acid increases glucagon like peptide-1 secretion via TGR5 activation in type 1-like diabetic rats. Biomed Pharmacother. 2017 Sep 4;95:599-604. [3]Li C, et al. Glycyrrhizin, a Direct HMGB1 Antagonist, Ameliorates Inflammatory Infiltration in a Model of Autoimmune Thyroiditis via Inhibition of TLR2-HMGB1 Signaling. Thyroid. 2017 May;27(5):722-731. [4]Xia Zhao, et al. A Simple Injectable Moldable Hydrogel Assembled from Natural Glycyrrhizic Acid with Inherent Antibacterial Activity. ACS Appl. Bio Mater. 2020, 3, 1, 648–653.
Smiles	C[C@]12[C@@](C(C=C3[C@]2(CC[C@]4(C)[C@@]3([H])C[C@](C(O)=O)(C)CC4)C)=O)([H])[C@@]5([C@@](C(C)([C@@H](O[C@]6([H])[C@@H]([C@H]([C@H](O)[C@@H](C(O)=O)O6)O)O[C@]7([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)C(O)=O)CC5)C)([H])CC1)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Glycyrrhizin
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Virus Protease
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	822.93
Product Description	Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.
Manufacturer - Research Area	Cancer; Metabolic Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)\|H2O : < 0.1 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection
Clinical information	Launched

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkt-Datenblatt anfordern

HY-N0184-100mg-safety-datasheet.pdf