Decursinol

ArtNr	HY-N4109-50mg
Hersteller	MedChem Express
CAS-Nr.	23458-02-8
Menge	50 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 20 mg 25 mg 50 mg 5 mg
Kategorie	Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	99.89
Citations	[1]Choi SS, et al. Antinociceptive mechanisms of orally administered decursinol in the mouse. Life Sci. 2003 Jun 13;73(4):471-85.\|[2]Son SH, et al. Decursin and decursinol from Angelica gigas inhibit the lung metastasis of murine colon carcinoma. Phytother Res. 2011 Jul;25(7):959-64.\|[3]Kang SY, et al. Decursinol and decursin protect primary cultured rat cortical cells from glutamate-induced neurotoxicity. J Pharm Pharmacol. 2007 Jun;59(6):863-70.\|[4]Li L, et al. Single oral dose pharmacokinetics of decursin, decursinol angelate, and decursinol in rats. Planta Med. 2013 Mar;79(3-4):275-80.
Smiles	O=C(O1)C=CC(C1=C2)=CC3=C2OC(C)(C)[C@@H](O)C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	23458-02-8
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Calcium Channel; JNK; MMP; PERK
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	246.262
Product Description	Decursinol is an orally active coumarin compound that can be isolated from the roots of Angelica gigas. Decursinol is also a metabolite of Decursin (HY-18981) and Decursinol angelate (HY-N4322). Decursinol exhibits multiple activities such as analgesic, antinociceptive, anti-inflammatory, antioxidant, antimetastatic, and neuroprotective effects. Decursinol can be used for research on diseases such as tumors and nervous system disorders[1][2][3][4].
Manufacturer - Research Area	Cancer; Inflammation/Immunology; Neurological Disease
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Cell Cycle/DNA Damage; MAPK/ERK Pathway; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Isoform	MMP-2; MMP-9
Clinical information	No Development Reported

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HY-N4109-50mg-safety-datasheet.pdf