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PE-Labeled Human HLA-C*05:01&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein (MHC-HM491TP)

PE-Labeled Human HLA-C*05:01&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein (MHC-HM491TP)

ArtNr	MHC-HM491TP-100UG
Hersteller	KactusBio
Menge	100 ug
Quantity options	100 ug 500 ug
Kategorie	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Adenocarcinoma Cytoskeleton By Organ Lung Cancer Colorectal Cancer Heart & Blood Cancer small GTPases Ras Subfamily
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	HIS, Avi
Dry ice	Yes
Sequence	Cys25-Ala366(HLA-C*05:01), Ile21-Met119(B2M) and GADGVGKSAL peptide
NCBI	AAD11469.1(HLA-C*05:01),P61769(B2M),GADGVGKSAL
Alias	MHC,KRAS,K-Ras 2,KRAS2,C-K-RAS,CFC2,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KRAS1,KRAS2,NS,NS3,RASK2,GTPase Kras,KI-RAS,RALD
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	HLA-C*05:01&B2M&KRAS G12D (GADGVGKSAL)
Manufacturer - Conjugate / Tag	C-His-Avi
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Description	Recombinant PE-Labeled Human HLA-C05:01&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. PE-Labeled Human HLA-C05:01&B2M&KRAS G12D (GADGVGKSAL) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Cys25-Ala366(HLA-C*05:01), Ile21-Met119(B2M) and GADGVGKSAL peptide.
Background	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS, 200mM L-Arginine (pH 7.4).
Biotinylated	no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

MHC-HM491TP-100UG-datasheet.pdf

MHC-HM491TP-100UG-safety-datasheet.pdf