BzATP triethylammonium salt

Non Antibodies

P2X7 receptors

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

1018, 97

An Agonist of P2X7 Receptors

Soluble up to 100 mM in water. Centrifuge all products before handling (10000 x g 5 min).

41116134

BzATP triethylammonium salt is an agonist of the purinergic P2X7 receptor, more potent than ATP, with EC50 varying from 0.7 to 285 µM, depending on receptor species, buffer composition, serum constituents and repeated exposure to ATP. Shows partial agonist activity on other P2X receptors. Can be used as a photoaffinity label for ATPase1-3.

Yes

BzATP triethylammonium salt is an agonist of the purinergic P2X7 receptor that is ten times more potent than ATP1. On rat P2X7 receptor, BzATP triethylammonium salt demonstrates an EC50 value of 6.8 µM2. The compound also shows partial agonist activity on other P2X receptors1.P2X receptors are a family of ion channels gated by ATP, a ligand that mediates numerous physiological functions. P2X receptors are widely localized in cell types of almost every origin, including neuronal, muscular, epithelial and immune, and have been shown to play a pivotal role in models of various pain conditions2.