Ethyl 2-chloro-2-(hydroxyimino)acetate

RT

151, 55

White to off-white powder

Ethyl 2-chloro-2-(hydroxyimino)acetate is an organic compound that contains a chloride group, two oxadiazole rings, and an ethyl group. It has been shown to bind to receptors on the surface of cells and act as a competitive antagonist. It has also been shown to inhibit influenza virus growth by binding to the receptor binding site on the virus surface. Ethyl 2-chloro-2-(hydroxyimino)acetate can be made synthetically or in nature by the reaction of formaldehyde with ammonia, which produces glutamic acid and hydrogen chloride gas. This molecule is able to react with sodium carbonate in water to produce ethyl chloroformate. The molecule has been shown to have cancerous effects when injected into rats.

Synonyms:
1-Ethyl oxalyl chloride 2-oxime; α-Chloroglyoxalic Acid Ethyl Ester Oxime; 2-Chloro-2-(hydroxyimino)acetic Acid Ethyl Ester; Ethylchloroximidoacetate

CAS No:
14337-43-0

Molecular Formula:
C4H6ClNO3

Molecular Weight:
151.55

Appearance:
White to off-white powder

Purity:
≥97%

NMR, CNMR, LC-MS:
Conforms to reference

Melting Point:
79-83°C

Solubility:
Methanol

Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at 4°C. Store under inert gas, Moisture Sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.