Sulfacetamide Sodium Monohydate

RT

254, 24

White solid

Sulfacetamide sodium monohydrate is a sulfa drug that is used in the treatment of infections caused by bacteria that are sensitive to sulfonamides. It is also used to reduce the symptoms of rosacea, a skin condition. Sulfacetamide sodium monohydrate inhibits microbial growth by disrupting microbial fatty acid synthesis and inhibiting bacterial growth through various mechanisms including hydrolysis by hydrochloric acid, metabolic disorders, or changes in water permeability. It has been shown to be an effective treatment for congestive heart failure due to its ability to increase the thickness of the glomerular basement membrane and inhibit erythrocyte adhesion. This drug is also useful as a topical agent for treating mild cases of radiation dermatitis and has high values as an anhydrous sodium sulfate substitute for wastewater treatment.

Synonyms:
N-[(4-Aminophenyl)sulfonyl]acetamide Monosodium Salt Monohydrate; N-Sulfanilylacetamide Monosodium Salt Monohydrate; N1-Acetylsulfanilamide Sodium Monohydrate; Sodium N-sulfanilylacetamide Monohydrate; Sodium Sulfacetamide Monohydrate; Sulamyd Sodium Monohydrate; Sulfacetamide Sodium Monohydrate

CAS Number:
6209-17-2

Molecular Formula:
C8H9N2NaO3S•H2O

Molecular Weight:
254.24

Appearance:
White solid

Purity:
≥99%

1H-NMR Spectrum:
Corresponds to structure

Solubility:
DMSO, Methanol (Sparingly)

Storage and Stability:
Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.