Progesterone Receptor Monoclonal Antibody

Antibody

Progesterone Receptor

PGR; PGR; PR; NR3C3; NR3C3

Anti-Progesterone Receptor [Murine MAb to fusion protein corresponding to aa 1-101 of human progesterone receptor, a member of the steroid family of nuclear receptors.]
This antibody recognizes human progesterone receptor (PgR), a member of the steroid family of nuclear receptors. PgR is found as a 94 kD protein (Form A) or a 120 kD protein (Form B). Binding of progesterone to its receptor results in a conformational change that allows dimerization and binding of the receptor to progesterone response elements and activated transcription. When bound to DNA, PgR can positively or negatively regulate gene transcription.

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