Vergleich

Recombinant human Beta-glucuronidase/GUSB protein

ArtNr NKM-ATGP3495-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug 5 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence LQGGMLYPQE SPSRECKELD GLWSFRADFS DNRRRGFEEQ WYRRPLWESG PTVDMPVPSS FNDISQDWRL RHFVGWVWYE REVILPERWT QDLRTRVVLR IGSAHSYAIV WVNGVDTLEH EGGYLPFEAD ISNLVQVGPL PSRLRITIAI NNTLTPTTLP PGTIQYLTDT SKYPKGYFVQ NTYFDFFNYA GLQRSVLLYT TPTTYIDDIT VTTSVEQDSG LVNYQISVKG SN
Citations Shipley JM., et al. (1993) Am J Hum Genet. 52:517-526.
Bell CE Jr., et al. (1977) J Clin Invest. 59:97-105.
NCBI NP_000172.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Beta-glucuronidase isoform 1,GUSB,BG,MPS7,Glucuronidase beta,Beta-G1
Similar products GUSB, BG, MPS7, Beta-glucuronidase isoform 1, ATGP3495-10ug, ATGP3495-20ug, ATGP3495-50ug, ATGP3495-100ug, ATGP3495-250ug, ATGP3495-500ug, ATGP3495-1mg, ATGP3495-10, ATGP3495-20, ATGP3495-50, ATGP3495-100, ATGP3495-250, ATGP3495-500, ATGP3495-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
73.4 kDa (635aa)
Description
GUSB, also known as beta-glucuronidase isoform 1, is a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans. It includes heparin sulfate, chondroitin sulfate and hyaluronan. Mutations in the GUSB are linked to mucopolysaccharidosis type VII. GUSB plays an important role in the degradation of dermatan and keratin sulfates. Recombinant human GUSB, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Signal Transduction
Domain
23-651aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Specific activity is > 4000pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1pmole of 4-Methylum-belliferyl-beta-D-glucosiduronic acid to 4-Methylumbelliferone per minute at 37C and pH3.5.
Predicted nterm
Leu23
Species of Protein
Human
Manufacturer - Search Terms
GUSB, Beta-glucuronidase isoform 1, GUSB, BG, MPS7, ATGP3495-10ug, ATGP3495-20ug, ATGP3495-50ug, ATGP3495-100ug, ATGP3495-250ug, ATGP3495-500ug, ATGP3495-1mg, ATGP3495-10, ATGP3495-20, ATGP3495-50, ATGP3495-100, ATGP3495-250, ATGP3495-500, ATGP3495-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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