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Recombinant human TRAILR2/TNFRSF10B protein

ArtNr NKM-ATGP3732-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence ITQQDLAPQQ RAAPQQKRSS PSEGLCPPGH HISEDGRDCI SCKYGQDYST HWNDLLFCLR CTRCDSGEVE LSPCTTTRNT VCQCEEGTFR EEDSPEMCRK CRTGCPRGMV KVGDCTPWSD IECVHKESGT KHSGEVPAVE ETVTSSPGTP ASPCS<LEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT K
Citations Finnberg NK., et al, (2016) Cancer Res. 76:700-712.
Shin GC., et al, (2016) Autophagy. 12:2451-2466.
NCBI NP_003833
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Tumor necrosis factor receptor superfamily member 10B isoform 1,TNFRSF10B,CD262,Death receptor 5,DR5,KILLER,KILLER/DR5,TRAIL receptor 2,TRAIL-R2,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,ZTNFR9
Similar products TNFRSF10B, TRAIL R2, ATGP3732-10ug, ATGP3732-20ug, ATGP3732-50ug, ATGP3732-100ug, ATGP3732-250ug, ATGP3732-500ug, ATGP3732-1mg, ATGP3732-10, ATGP3732-20, ATGP3732-50, ATGP3732-100, ATGP3732-250, ATGP3732-500, ATGP3732-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Conjugate / Tag
hIgG-His-Tag
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
43.9 kDa (394aa)
Description
TNFRSF10B, also known as tumor necrosis factor receptor superfamily member 10B isoform 1, is a member of receptors for the cytotoxic ligand TNFSF10/TRAIL. It can be activated by tumor necrosis factor-related apoptosis inducing ligand, and transduces an apoptosis signal. This protein promotes the activation of NF-kappa-B. Defects in this protein causes of head and neck squamous cell carcinomas. Recombinant human TNFRSF10B protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Apoptosis
Domain
56-210aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its ability to inhibit cytotoxicity using Jurkat human acute T cell leukemia cells. The ED50 range ≤5ng/ml with Human TRAIL.
Predicted nterm
Ile56
Species of Protein
Human
Manufacturer - Search Terms
TRAIL R2, TNFRSF10B, ATGP3732-10ug, ATGP3732-20ug, ATGP3732-50ug, ATGP3732-100ug, ATGP3732-250ug, ATGP3732-500ug, ATGP3732-1mg, ATGP3732-10, ATGP3732-20, ATGP3732-50, ATGP3732-100, ATGP3732-250, ATGP3732-500, ATGP3732-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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