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Recombinant mouse Neutrophil Elastase/ELA2 protein

ArtNr NKM-ATGP3873-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Mouse (Murine, Mus musculus)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence SEIVGGRPAR PHAWPFMASL QRRGGHFCGA TLIARNFVMS AAHCVNGLNF RSVQVVLGAH DLRRQERTRQ TFSVQRIFEN GFDPSQLLND IVIIQLNGSA TINANVQVAQ LPAQGQGVGD RTPCLAMGWG RLGTNRPSPS VLQELNVTVV TNMCRRRVNV CTLVPRRQAG ICFGDSGGPL VCNNLVQGID SFIRGGCGSG LYPDAFAPVA EFADWINSII RSHNDHLLTH PK
Citations Wiesmeier M., et al, (2016) PLoS ONE 11:e0168055.
Sturrock A., et al, (1998) Cytogenet. Cell Genet. 83:104-108.
NCBI NP_056594.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Elane,Ela2,F430011M15Rik,NE,Neutrophil elastase,Elastase-2,Leukocyte elastase
Similar products Neutrophil Elastase, ELA2, ATGP3873-10ug, ATGP3873-20ug, ATGP3873-50ug, ATGP3873-100ug, ATGP3873-250ug, ATGP3873-500ug, ATGP3873-1mg, ATGP3873-10, ATGP3873-20, ATGP3873-50, ATGP3873-100, ATGP3873-250, ATGP3873-500, ATGP3873-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
26.8 kDa (245aa)
Description
Neutrophil Elastase, also known as polymorphonuclear leukocyte eslastase, is a serine protease that classified as the chymotrypsin family. This protein breaks down elastin, an elastic fiber together with collagen and determines the mechanical properties of connective tissue. The neutrophil form breaks down the Outer membrane protein A (OmpA) of E. coli and other Gram-negative bacteria. Also, this protein is inhibited by the acute-phase protein alpha 1-antitrypsin (A1AT), which binds almost irreversibly to the active site of elastase and trypsin. A1AT is normally secreted by the liver cells into the serum. Alpha-1-antitrypsin deficiency (A1AD) leads to uninhibited destruction of elastic fiber by elastase. Recombinant Mouse Neutrophil Elastase, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 30% glycerol
Antigen Species
Mouse
Gene Category
Immunology
Domain
27-265aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm
Ser27
Species of Protein
Mouse
Manufacturer - Search Terms
Neutrophil Elastase, ELA2, ATGP3873-10ug, ATGP3873-20ug, ATGP3873-50ug, ATGP3873-100ug, ATGP3873-250ug, ATGP3873-500ug, ATGP3873-1mg, ATGP3873-10, ATGP3873-20, ATGP3873-50, ATGP3873-100, ATGP3873-250, ATGP3873-500, ATGP3873-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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