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Recombinant mouse Lactate Dehydrogenase A/LDHA protein

ArtNr NKM-ATGP4118-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Mouse (Murine, Mus musculus)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence MATLKDQLIV NLLKEEQAPQ NKITVVGVGA VGMACAISIL MKDLADELAL VDVMEDKLKG EMMDLQHGSL FLKTPKIVSS KDYCVTANSK LVIITAGARQ QEGESRLNLV QRNVNIFKFI IPNIVKYSPH CKLLIVSNPV DILTYVAWKI SGFPKNRVIG SGCNLDSARF RYLMGERLGV HALSCHGWVL GEHGDSSVPV WSGVNVAGVS LKSLNPELGT DADKEQWKEV HK
Citations Rong Y., et al. (2013) Tumour Biol. 34(3):1523-1530.
Merkle S., et al. (1992) Genetics. 131(2):413-421.
NCBI NP_034829
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias L-lactate dehydrogenase A chain isoform 1,LDH muscle subunit (LDH-M),Ldha,17R2,Ldh1,Ldhm,LDH-A,LDH muscle smb
Lieferbar
Manufacturer - Type
Proteins
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Manufacturer - Category
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
37.5 kDa (340aa)
Description
Ldha, also known as L-lactate dehydrogenase A chain isoform 1, is a member of the LDH/MDH superfamily and LDH family. It catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. This protein is found predominantly in muscle tissue. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It plays an important role in the development, invasion and metastasis of malignancies. Recombinant mouse Ldha, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Mouse
Gene Category
Signal Transduction, Metabolism
Domain
1-332aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Specific activity is > 250unit/mg, and is defined as the Amount of enzyme that convert 1.0 umole of pyruvate to L-lactate and per minute at pH 7.5 at 37℃.
Additional Comment Only
ATGP3341 has been replaced with a catalog number ATGP4118.
Predicted nterm
Met1
Species of Protein
Mouse
Manufacturer - Search Terms
ATGP4118-10ug, ATGP4118-20ug, ATGP4118-50ug, ATGP4118-100ug, ATGP4118-250ug, ATGP4118-500ug, ATGP4118-1mg, ATGP4118-010, ATGP4118-020, ATGP4118-050, ATGP4118-100, ATGP4118-250, ATGP4118-500, ATGP4118-01M, ATGP3341-10ug, ATGP3341-20ug, ATGP3341-50ug, ATGP3341-100ug, ATGP3341-250ug, ATGP3341-500ug, ATGP3341-1mg, ATGP3341-010, ATGP3341-020, ATGP3341-050, ATGP3341-100, ATGP3341-250, ATGP3341-500, ATGP3341-01M
Manufacturer - Similar Names
ATGP4118-10ug, ATGP4118-20ug, ATGP4118-50ug, ATGP4118-100ug, ATGP4118-250ug, ATGP4118-500ug, ATGP4118-1mg, ATGP4118-010, ATGP4118-020, ATGP4118-050, ATGP4118-100, ATGP4118-250, ATGP4118-500, ATGP4118-01M, ATGP3341-10ug, ATGP3341-20ug, ATGP3341-50ug, ATGP3341-100ug, ATGP3341-250ug, ATGP3341-500ug, ATGP3341-1mg, ATGP3341-010, ATGP3341-020, ATGP3341-050, ATGP3341-100, ATGP3341-250, ATGP3341-500, ATGP3341-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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