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Human FABP4/A-FABP antibody

ArtNr NKM-AFA0920-50ul
Hersteller NKMAX
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, ICC, ELISA
Clon 3F4
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Konjugat/Tag Unconjugated
Citations Furuhashi M., et al., (2007) Nature. 21.447(7147):959-65.
Shum BO, et al., (2006) J Clin Invest. 116(8):2183-92.
NCBI NP_001433
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Fatty acid binding protein 4,fatty acid binding protein 4 adipocyte,A-FABP,aP2
Lieferbar
Manufacturer - Type
Antibodies
Manufacturer - Applications
ELISA, WB, ICC/IF
Manufacturer - Category
Monoclonal Antibody
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description
FABP4 (Fatty acid binding protein 4) is expressed in adipocytes and macrophages, and integrates inflammatory and metabolic responses. FABP4 is thought to regulate fatty acid uptake, release, and storage in adipocytes and participates in systemic glucose homeostasis and in macrophage responses in atherosclerosis. Blocking this protein either through genetic engineering or drugs has the possibility of treating heart disease, diabetes, asthma, obesity, and fatty liver disease.
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen
Recombinant human FABP4 (1-132aa) purified from E. coli
Ab Usage
The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species
Human
Clonality
Monoclonal
Ab Purification Comment
By protein-G affinity chromatography
Gene Category
Enzymes & Proteases
Manufacturer - Search Terms
IL-1A, IL1A, IL-1 alpha, IL1 alpha, IL 1A, IL 1 alpha, IL 1 A, Hematopoietin-1, Hematopoietin1, Hematopoietin 1, Fatty acid binding protein 4 adipocyte, Fatty acid binding protein 4, FABP4, AP2, ALBP, A-FABP, AFABP, A FABP, AFA0920-10ug, AFA0920-20ug, AFA0920-50ug, AFA0920-100ug, AFA0920-250ug, AFA0920-500ug, AFA0920-1mg, AFA0920-010, AFA0920-020, AFA0920-050, AFA0920-100, AFA0920-250, AFA0920-500, AFA0920-01M
Manufacturer - Similar Names
IL-1A, IL1A, IL-1 alpha, IL1 alpha, IL 1A, IL 1 alpha, IL 1 A, Hematopoietin-1, Hematopoietin1, Hematopoietin 1, Fatty acid binding protein 4 adipocyte, Fatty acid binding protein 4, FABP4, AP2, ALBP, A-FABP, AFABP, A FABP, AFA0920-10ug, AFA0920-20ug, AFA0920-50ug, AFA0920-100ug, AFA0920-250ug, AFA0920-500ug, AFA0920-1mg, AFA0920-010, AFA0920-020, AFA0920-050, AFA0920-100, AFA0920-250, AFA0920-500, AFA0920-01M
IF Comment
ICC/IF analysis of FABP4 in HeLa cells. The cell was stained with AFA0920 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
WB Comment
The tissue lysates of mouse heart (40ug) was resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human FABP4 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. The tissue lysates of mouse adipose (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human FABP4 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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