Vergleich

Human Caveolin-1 antibody

ArtNr NKM-ATGA0195-100ul
Hersteller NKMAX
Menge 100 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, ICC, ELISA
Clon AT4C1
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2b Kappa
Konjugat/Tag Unconjugated
Citations Van Meer, G., et al. (2008) Nat Rev Mol Cell Biol. 9: 112-124.
Todeschini, R.A. et al. (2008) Biochim Biophy Acta 1780: 421-433.
Lajoie, P et al. (2007) J Cell Mol Med 11: 644-653.
NCBI NP_001744
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias VIP 21,CAV,CAV 1,CAV1,caveolae protein 22 kD,caveolin 1 alpha isoform,caveolin 1 beta isoform,Caveolin 1 caveolae protein 22kDa,Caveolin1,cell growth-inhibiting protein 32,MSTP085,OTTHUMP00000025031,VIP 21,VIP21
Similar products Caveolin1, ATGA0195-10ug, ATGA0195-20ug, ATGA0195-50ug, ATGA0195-100ug, ATGA0195-250ug, ATGA0195-500ug, ATGA0195-1mg, ATGA0195-10, ATGA0195-20, ATGA0195-50, ATGA0195-100, ATGA0195-250, ATGA0195-500, ATGA0195-1
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Manufacturer - Type
Monoclonal Antibody
Manufacturer - Applications
ELISA, WB, ICC/IF
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description
The identification of caveolin-1 (CAV1) as the main structural component of caveolae, together with the finding that CAV1 might serve as a molecular organizer for membrane multiprotein complexes involved in cellular traffic, endo-and transcytosis, cell adhesion and signal transduction prompted a new impulse in the research on these intracellular organells. One of the properties of CAV1 was its insolubility in cold non-ionic detergents together with apical markers in epithelial cell. Also, cholesterol is essential for caveolae formation and maintenance, and caveolae structure is highly sensitive to cholesterol depletion or treatment with cholesterol binding drugs. CAV1 tightly and specifically binds free cholesterol and artificial cholesterol containing vesicles.
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen
Recombinant human CAV1 (1-104aa) purified from E. coli
Ab Usage
The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species
Human
Clonality
Monoclonal
Ab Purification Comment
By protein-G affinity chromatography
Gene Category
Signal Transduction
Manufacturer - Search Terms
Caveolin1, ATGA0195-10ug, ATGA0195-20ug, ATGA0195-50ug, ATGA0195-100ug, ATGA0195-250ug, ATGA0195-500ug, ATGA0195-1mg, ATGA0195-10, ATGA0195-20, ATGA0195-50, ATGA0195-100, ATGA0195-250, ATGA0195-500, ATGA0195-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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