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Human Cathepsin Z antibody

Human Cathepsin Z antibody

ArtNr	NKM-ATGA0304-50ul
Hersteller	NKMAX
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Antibodies Cell Biology Cell Status Apoptosis Western Blot ELISA Immunocytochemistry Primary Antibodies By Organ Immunostaining Uterine, Ovarian & Cervical Cancer Immunochemistry
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, ICC, ELISA
Clon	AT6G11
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Konjugat/Tag	Unconjugated
Citations	Pungercar. J., et al. (2000) Pflugers Arch 439: R119-R121 Pungercar. J. and Ivanovski. G. (2000) Pflugers Arch 439: R116-R118 Naegler. D.K., et al. (1999) Biochemistry 38: 12648-12654
NCBI	NP_001327
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Carboxypeptidase LB,Cathepsin B2,Cathepsin IV,Cathepsin P,Cathepsin X,Cathepsin Y,Cathepsin Z,Cathepsin Z preproprotein,Cathepsin Z1,CatX,CTSP,CTSX,CTSZ,Cysteine-type carboxypeptidase,Lysosomal carboxypeptidase B
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Manufacturer - Type	Antibodies
Manufacturer - Applications	ELISA, WB, ICC/IF
Manufacturer - Category	Monoclonal Antibody
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description	CTSZ (Cathepsin Z), also known as Cathepsin X and Cathepsin P, is 303 amino acid protein. It is lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity. This gene is widely expressed in cancer cell lines, primary tumors. CTSZ may be involved in tumor progression. And, CTSZ plays a role in normal intracellular protein degradation
Concentration	1mg/ml (determined by BCA assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen	Recombinant human CTSZ (62-303aa) purified from E. coli
Ab Usage	The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.
Antigen Species	Human
Clonality	Monoclonal
Ab Purification Comment	By protein-A affinity chromatography
Gene Category	Tags & Cell Markers
Manufacturer - Search Terms	Carboxypeptidase LB, Cathepsin B2, Cathepsin IV, Cathepsin P, Cathepsin X, Cathepsin X Z P, Cathepsin X, Z, P, Cathepsin X/Z/P, Cathepsin XZP, Cathepsin Y, Cathepsin Z, Cathepsin Z preproprotein, Cathepsin Z1, Cathepsin-IV, Cathepsin-X, Cathepsin-Y, Cathepsin-Z, Cathepsin-Z1, Cathepsin-B2, CatX, CTSP, CTSX, CTSZ, Cysteine-type carboxypeptidase, Lysosomal carboxypeptidase B, ATGA0304-10ug, ATGA0304-20ug, ATGA0304-50ug, ATGA0304-100ug, ATGA0304-250ug, ATGA0304-500ug, ATGA0304-1mg, ATGA0304-010, ATGA0304-020, ATGA0304-050, ATGA0304-100, ATGA0304-250, ATGA0304-500, ATGA0304-01M
Manufacturer - Similar Names	Carboxypeptidase LB, Cathepsin B2, Cathepsin IV, Cathepsin P, Cathepsin X, Cathepsin X Z P, Cathepsin X, Z, P, Cathepsin X/Z/P, Cathepsin XZP, Cathepsin Y, Cathepsin Z, Cathepsin Z preproprotein, Cathepsin Z1, Cathepsin-IV, Cathepsin-X, Cathepsin-Y, Cathepsin-Z, Cathepsin-Z1, Cathepsin-B2, CatX, CTSP, CTSX, CTSZ, Cysteine-type carboxypeptidase, Lysosomal carboxypeptidase B, ATGA0304-10ug, ATGA0304-20ug, ATGA0304-50ug, ATGA0304-100ug, ATGA0304-250ug, ATGA0304-500ug, ATGA0304-1mg, ATGA0304-010, ATGA0304-020, ATGA0304-050, ATGA0304-100, ATGA0304-250, ATGA0304-500, ATGA0304-01M
IF Comment	ICC/IF analysis of CTSZ in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CTSZ antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
WB Comment	The cell lysates of HeLa (40ug) and SW480 (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CTSZ antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. The recombinant proteins (20ng) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CTSZ antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1. : Recombinant Human CTSB Lane 2. : Recombinant Human CTSD Lane 3. : Recombinant Human CTSE Lane 4. : Recombinant Human CTSF Lane 5. : Recombinant Human CTSH Lane 6. : Recombinant Human CTSK Lane 7. : Recombinant Human CTSL Lane 8. : Recombinant Human CTSS Lane 9. : Recombinant Human CTSW Lane 10. : Recombinant Human CTSZ

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