Vergleich

Human Fumarase/FH antibody

ArtNr NKM-ATGA0366-50ul
Hersteller NKMAX
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, FC, ICC, ELISA
Clon AT3F6
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a Kappa
Konjugat/Tag Unconjugated
Citations Lehtonen R., et al. (2003) J Med Genet. 40(3): e19.
Toro JR., et al. (2003) Am J Hum Genet. 73(1): 95-106.
NCBI NP_000134
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Fumarate hydratase,FH,HLRCC,LRCC,MCL,MCuL1,Fumarate hydratase Fumarase,Fumarate hydratase mitochondrial,MCuL 1,Multiple hereditary cutaneous leiomyomata.
Similar products Fumarase, FH, Fumarate hydratase, MCL, HLRCC, LRCC, Fumarate hydratase mitochondrial, Multiple hereditary cutaneous leiomyomata., MCuL1, Fumarate hydratase Fumarase, MCuL 1, ATGA0366-10ug, ATGA0366-20ug, ATGA0366-50ug, ATGA0366-100ug, ATGA0366-250ug, ATGA0366-500ug, ATGA0366-1mg, ATGA0366-10, ATGA0366-20, ATGA0366-50, ATGA0366-100, ATGA0366-250, ATGA0366-500, ATGA0366-1
Lieferbar
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Applications
ELISA, WB, ICC/IF, FACS
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description
Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor.
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen
Recombinant human Fumarase (44-510aa) purified from E. coli
Ab Usage
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species
Human
Clonality
Monoclonal
Ab Purification Comment
By protein-A affinity chromatography
Gene Category
Cell Cycle
Manufacturer - Search Terms
Fumarase, Fumarate hydratase, FH, HLRCC, LRCC, MCL, MCuL1, Fumarate hydratase Fumarase, Fumarate hydratase mitochondrial, MCuL 1, Multiple hereditary cutaneous leiomyomata., ATGA0366-10ug, ATGA0366-20ug, ATGA0366-50ug, ATGA0366-100ug, ATGA0366-250ug, ATGA0366-500ug, ATGA0366-1mg, ATGA0366-10, ATGA0366-20, ATGA0366-50, ATGA0366-100, ATGA0366-250, ATGA0366-500, ATGA0366-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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