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Human Otubain-1/OTUB1 antibody

ArtNr NKM-ATGA0380-50ul
Hersteller NKMAX
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, ICC, ELISA
Clon AT17E10
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Konjugat/Tag Unconjugated
Citations Balakirev MY., et al. (2003) EMBO Rep. 4(5): 5175-5122.
Soares L., et al. (2004) Nat Immunol. 5(1): 45-54.
NCBI NP_060140
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias ubiquitin thioesterase Otubain 1,OTB1,OTu1,ubiquitin thioesterase Otubain 1 Deubiquitinating enzyme OTuB1,OTu domain containing ubiquitin aldehyde binding protein 1,Otubain 1,ubiquitin specific processing protease OTuB1,ubiquitin thioesterase OTuB1.
Similar products OTUB1, OTB1, Otubain 1, Otubain1, ubiquitin thioesterase Otubain 1, OTu1, ubiquitin thioesterase Otubain 1 Deubiquitinating enzyme OTuB1, OTu domain containing ubiquitin aldehyde binding protein 1, ubiquitin specific processing protease OTuB1, ubiquitin thioesterase OTuB1., ATGA0380-10ug, ATGA0380-20ug, ATGA0380-50ug, ATGA0380-100ug, ATGA0380-250ug, ATGA0380-500ug, ATGA0380-1mg, ATGA0380-10, ATGA0380-20, ATGA0380-50, ATGA0380-100, ATGA0380-250, ATGA0380-500, ATGA0380-1
Lieferbar
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Applications
ELISA, WB, ICC/IF
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description
Otubain 1, also known as OTUB1, is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases and inhibits cytokine gene transcription in the immune system via its interaction with an ubiquitin protease and E3 ubiquitin ligase. This protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function of polyubiquitin chain growth.
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen
Recombinant human OTUB1 (1-271aa) purified from E. coli
Ab Usage
The antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species
Human
Clonality
Monoclonal
Ab Purification Comment
By protein-A affinity chromatography
Gene Category
Enzymes & Proteases
Manufacturer - Search Terms
Otubain1, OTUB1, ubiquitin thioesterase Otubain 1, OTB1, OTu1, ubiquitin thioesterase Otubain 1 Deubiquitinating enzyme OTuB1, OTu domain containing ubiquitin aldehyde binding protein 1, Otubain 1, ubiquitin specific processing protease OTuB1, ubiquitin thioesterase OTuB1., ATGA0380-10ug, ATGA0380-20ug, ATGA0380-50ug, ATGA0380-100ug, ATGA0380-250ug, ATGA0380-500ug, ATGA0380-1mg, ATGA0380-10, ATGA0380-20, ATGA0380-50, ATGA0380-100, ATGA0380-250, ATGA0380-500, ATGA0380-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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