« Zurück
Startseite /
Human SOD1/Cu-Zn SOD antibody

Human SOD1/Cu-Zn SOD antibody

ArtNr	NKM-ATGA0405-50ul
Hersteller	NKMAX
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Neuroscience Metabolism Diabetes Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies Cell Biology Cell Status Cell Metabolism Flow Cytometry Western Blot ELISA Immunocytochemistry Oxidative Stress Primary Antibodies Immunostaining Immunochemistry
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, ICC, ELISA
Clon	AT6F1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Konjugat/Tag	Unconjugated
Citations	Deng HX., et al. (1993) Science. 261(5124): 1047-51. Valentine JS., et al. (2003) Proc Natl Acad Sci USA. 100(7): 3617-22. Rosen DR., et al. (1993) Nature. 362(6415): 59-62.
NCBI	NP_000445
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	SOD1, Cu-Zn SOD, ATGA0405-10ug, ATGA0405-20ug, ATGA0405-50ug, ATGA0405-100ug, ATGA0405-250ug, ATGA0405-500ug, ATGA0405-1mg, ATGA0405-10, ATGA0405-20, ATGA0405-50, ATGA0405-100, ATGA0405-250, ATGA0405-500, ATGA0405-1
Lieferbar
Manufacturer - Type	Antibodies
Manufacturer - Applications	ELISA, WB, ICC/IF, FACS
Manufacturer - Category	Monoclonal Antibody
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description	Cu/Zn superoxide dismutase (SOD1), is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. SOD1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. Also over 100 distinct SOD1 inherited mutations have been identified in the familial form of amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear.
Concentration	1mg/ml (determined by BCA assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen	Recombinant human SOD1 (1-154aa) purified from E. coli
Ab Usage	The antibody has been tested by ELISA, Western blot, ICC/IF and FACS analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species	Human
Clonality	Monoclonal
Ab Purification Comment	By protein-A affinity chromatography
Gene Category	Signal Transduction
Manufacturer - Search Terms	SOD1, Cu-Zn SOD, ATGA0405-10ug, ATGA0405-20ug, ATGA0405-50ug, ATGA0405-100ug, ATGA0405-250ug, ATGA0405-500ug, ATGA0405-1mg, ATGA0405-10, ATGA0405-20, ATGA0405-50, ATGA0405-100, ATGA0405-250, ATGA0405-500, ATGA0405-1
Manufacturer - Alternative Names	Superoxide dismutase 1 soluble, ALS, SOD, ALS1, IPOA, Cu-Zn superoxide dismutase, Superoxide dismutase 1 soluble, SOD1, Superoxide dismutase 1, soluble ALS 1, Amyotrophic lateral sclerosis 1 Amyotrophic lateral sclerosis 1 adult, Cu/Zn SOD, Cu/Zn superoxide dismutase, Homodimer, Indophenoloxidase A, Mn superoxide dismutase, SOD 1, SOD soluble, SOD2, SODC, Superoxide dismutase 1 soluble, Superoxide dismutase Cu Zn, Superoxide dismutase cystolic
IF Comment	ICC/IF analysis of SOD1 in Hep3B cells. The cell was stained with ATGA0405 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
WB Comment	The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human SOD1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1. : A549 cell lysate Lane 2. : A431 cell lysate Lane 3. : 293T cell lysate Lane 4. : PC3 cell lysate Lane 5. : U87MG cell lysate The recombinant proteins (20ng) of SOD two isoform were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human SOD1 (1:1000). Lane 1 : Recombinant protein SOD1 Lane 2 : Recombinant protein SOD2
FACS Comment	Flow cytometry analysis of SOD1 in Hep3B cell line, staining at 2-5ug for 1x10^6cells (red line). The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was mouse IgG (black line).

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

NKM-ATGA0405-50ul-datasheet.pdf

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 50 ul

lieferbar

Lieferung vsl. bis 04.12.2025

Express-Lieferung: 10 Tage sparen

Vergleichen

Auf den Wunschzettel

Angebot anfordern