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Human Thioredoxin Reductase 1/TRXR1 antibody

Human Thioredoxin Reductase 1/TRXR1 antibody

ArtNr	NKM-ATGA0451-50ul
Hersteller	NKMAX
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Cell Biology Cell Status Senescence Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, ICC, ELISA
Clon	AT30F1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Konjugat/Tag	Unconjugated
Citations	Ma X., et al. (2002) J Biol Chem. 277(25): 22460-8. Javvadi P (2010) Cancer Res. 70(5): 1941-50.
NCBI	NP_001087240
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	GRIM 12, KDRF, KM 102 derived reductase like factor, MGC9145, Oxidoreductase, Thioredoxin reductase, Thioredoxin reductase 1, Thioredoxin reductase 1 cytoplasmic, Thioredoxin reductase 1 Gene associated with retinoid IFN induced mortality 12 protein, Thioredoxin reductase GRIM 12, TR, TR 1, TRXR 1, TXNR, TXNRD 1
Similar products	TXNRD1, TR1, TR, Thioredoxin reductase, GRIM-12, MGC9145, TRXR1, TXNR, TR 1, Thioredoxin reductase 1, GRIM12, KDRF, Oxidoreductase, TRXR-1, TR-1, GRIM 12, KM 102 derived reductase like factor, Thioredoxin reductase 1 cytoplasmic, Thioredoxin reductase 1 Gene associated with retinoid IFN induced mortality 12 protein, Thioredoxin reductase GRIM 12, Thioredoxin reductase GRIM12, TRXR 1, TXNRD 1, TXNRD-1, ATGA0451-10ug, ATGA0451-20ug, ATGA0451-50ug, ATGA0451-100ug, ATGA0451-250ug, ATGA0451-500ug, ATGA0451-1mg, ATGA0451-010, ATGA0451-020, ATGA0451-050, ATGA0451-100, ATGA0451-250, ATGA0451-500, ATGA0451-01M
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Manufacturer - Type	Monoclonal Antibody
Manufacturer - Applications	ELISA, WB, ICC/IF
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description	TXNRD1, also known as Thioredoxin reductase 1, is a part of a selenium-containing pyridine nucleotidedisulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val-Asn-Val-Gly-Cys. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.
Concentration	1mg/ml (determined by BCA assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen	Recombinant human TXNRD1 (161-647aa) purified from E. coli
Ab Usage	The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species	Human
Clonality	Monoclonal
Ab Purification Comment	By protein-A affinity chromatography
Gene Category	Signal Transduction
Manufacturer - Search Terms	GRIM 12, GRIM12, GRIM-12, KDRF, KM 102 derived reductase like factor, MGC9145, Oxidoreductase, Thioredoxin reductase, Thioredoxin reductase 1, Thioredoxin reductase 1 cytoplasmic, Thioredoxin reductase 1 Gene associated with retinoid IFN induced mortality 12 protein, Thioredoxin reductase GRIM 12, Thioredoxin reductase GRIM12, TR, TR 1, TR1, TR-1, TRXR 1, TRXR1, TRXR-1, TXNR, TXNRD 1, TXNRD1, TXNRD-1, ATGA0451-10ug, ATGA0451-20ug, ATGA0451-50ug, ATGA0451-100ug, ATGA0451-250ug, ATGA0451-500ug, ATGA0451-1mg, ATGA0451-010, ATGA0451-020, ATGA0451-050, ATGA0451-100, ATGA0451-250, ATGA0451-500, ATGA0451-01M
Manufacturer - Alternative Names	GRIM 12, KDRF, KM 102 derived reductase like factor, MGC9145, Oxidoreductase, Thioredoxin reductase, Thioredoxin reductase 1, Thioredoxin reductase 1 cytoplasmic, Thioredoxin reductase 1 Gene associated with retinoid IFN induced mortality 12 protein, Thioredoxin reductase GRIM 12, TR, TR 1, TRXR 1, TXNR, TXNRD 1

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Menge: 50 ul

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Lieferung vsl. bis 31.07.2025

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