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Human Thioredoxin Reductase 1/TRXR1 antibody

ArtNr NKM-ATGA0451-50ul
Hersteller NKMAX
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, ICC, ELISA
Clon AT30F1
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2b Kappa
Konjugat/Tag Unconjugated
Citations Ma X., et al. (2002) J Biol Chem. 277(25): 22460-8.
Javvadi P (2010) Cancer Res. 70(5): 1941-50.
NCBI NP_001087240
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias GRIM 12, KDRF, KM 102 derived reductase like factor, MGC9145, Oxidoreductase, Thioredoxin reductase, Thioredoxin reductase 1, Thioredoxin reductase 1 cytoplasmic, Thioredoxin reductase 1 Gene associated with retinoid IFN induced mortality 12 protein, Thioredoxin reductase GRIM 12, TR, TR 1, TRXR 1, TXNR, TXNRD 1
Similar products TXNRD1, TR1, TR, Thioredoxin reductase, GRIM-12, MGC9145, TRXR1, TXNR, TR 1, Thioredoxin reductase 1, GRIM12, KDRF, Oxidoreductase, TRXR-1, TR-1, GRIM 12, KM 102 derived reductase like factor, Thioredoxin reductase 1 cytoplasmic, Thioredoxin reductase 1 Gene associated with retinoid IFN induced mortality 12 protein, Thioredoxin reductase GRIM 12, Thioredoxin reductase GRIM12, TRXR 1, TXNRD 1, TXNRD-1, ATGA0451-10ug, ATGA0451-20ug, ATGA0451-50ug, ATGA0451-100ug, ATGA0451-250ug, ATGA0451-500ug, ATGA0451-1mg, ATGA0451-010, ATGA0451-020, ATGA0451-050, ATGA0451-100, ATGA0451-250, ATGA0451-500, ATGA0451-01M
Lieferbar
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Applications
ELISA, WB, ICC/IF
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description
TXNRD1, also known as Thioredoxin reductase 1, is a part of a selenium-containing pyridine nucleotidedisulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val-Asn-Val-Gly-Cys. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen
Recombinant human TXNRD1 (161-647aa) purified from E. coli
Ab Usage
The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species
Human
Clonality
Monoclonal
Ab Purification Comment
By protein-A affinity chromatography
Gene Category
Signal Transduction
Manufacturer - Search Terms
GRIM 12, GRIM12, GRIM-12, KDRF, KM 102 derived reductase like factor, MGC9145, Oxidoreductase, Thioredoxin reductase, Thioredoxin reductase 1, Thioredoxin reductase 1 cytoplasmic, Thioredoxin reductase 1 Gene associated with retinoid IFN induced mortality 12 protein, Thioredoxin reductase GRIM 12, Thioredoxin reductase GRIM12, TR, TR 1, TR1, TR-1, TRXR 1, TRXR1, TRXR-1, TXNR, TXNRD 1, TXNRD1, TXNRD-1, ATGA0451-10ug, ATGA0451-20ug, ATGA0451-50ug, ATGA0451-100ug, ATGA0451-250ug, ATGA0451-500ug, ATGA0451-1mg, ATGA0451-010, ATGA0451-020, ATGA0451-050, ATGA0451-100, ATGA0451-250, ATGA0451-500, ATGA0451-01M
Manufacturer - Alternative Names
GRIM 12, KDRF, KM 102 derived reductase like factor, MGC9145, Oxidoreductase, Thioredoxin reductase, Thioredoxin reductase 1, Thioredoxin reductase 1 cytoplasmic, Thioredoxin reductase 1 Gene associated with retinoid IFN induced mortality 12 protein, Thioredoxin reductase GRIM 12, TR, TR 1, TRXR 1, TXNR, TXNRD 1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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