Recombinant human DKK1 protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Dickkopf-related protein 1, also known as Dkk-1, is a member of the Dkk protein family including Dkk-1, 2, 3 and -4. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated level of Dkk-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. Recombinant human Dkk-1 protein, fused to His-tag at C-terminus, was expressed ininsect cell using baculovirus expression system and purified by using conventional chromatography.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 50% glycerol, 2mM DTT, 2mM EDTA, 0.1mM PMSF

Signal Transduction

< 1 EU per 1ug of protein (determined by LAL method)

Human