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Recombinant human DKK1 protein

ArtNr NKM-ATGP0269-10ug
Hersteller NKMAX
Menge 10 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <ADP>TLNSVLN SNAIKNLPPP LGGAAGHPGS AVSAAPGILY PGGNKYQTID NYQPYPCAED EECGTDEYCA SPTRGGDAGV QICLACRKRR KRCMRHAMCC PGNYCKNGIC VSSDQNHFRG EIEETITESF GNDHSTLDGY SRRTTLSSKM YHTKGQEGSV CLRSSDCASG LCCARHFWSK ICKPVLKEGQ VCTKHRRKGS HGLEIFQRCY CGEGLSCRIQ KDHHQASNSS
Citations Krupnik, V.E. et al. (1999) Gene 238:301-13.
Nusse, R. et al. (2001) Nature 411:255-6.
Mao, J. et al. (2001) Mol. Cell 7:801-9.

Hino M, et al. Transforming growth factor-β1 induces invasion ability of HSC-4 human oral squamous cell carcinoma cells through the Slug/Wnt-5b/MMP-10 signalling axis. (J Biochem. 2016){https://pubmed.ncbi.nlm.nih.gov/26861993/}
NCBI NP_036374
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Dickkopf WNT signaling pathway inhibitor 1,Dickkopf-related protein 1,Dickkopf-1,Dkk-1,SK
Similar products DKK1, DKK-1, SK, Xenopus laevis, Dickkopf-related protein 1, Dickkopf-1, hDkk-1, Dickkopf 1, Dickkopf homolog 1, Dickkopf related protein 1, DKK 1, hDkk 1, hDkk1, Dickkopf 1 homolog, Dickkopf 1 like, Dickkopf-related protein 1 Dickkopf 1, ATGP0269-10ug, ATGP0269-20ug, ATGP0269-50ug, ATGP0269-100ug, ATGP0269-250ug, ATGP0269-500ug, ATGP0269-1mg, ATGP0269-010, ATGP0269-020, ATGP0269-050, ATGP0269-100, ATGP0269-250, ATGP0269-500, ATGP0269-01M
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
27.8 kDa (253aa)
Description
Dickkopf-related protein 1, also known as Dkk-1, is a member of the Dkk protein family including Dkk-1, 2, 3 and -4. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated level of Dkk-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. Recombinant human Dkk-1 protein, fused to His-tag at C-terminus, was expressed ininsect cell using baculovirus expression system and purified by using conventional chromatography.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 50% glycerol, 2mM DTT, 2mM EDTA, 0.1mM PMSF
Antigen Species
Human
Gene Category
Signal Transduction
Domain
32-266aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
Dickkopf 1, Dickkopf 1 homolog, Dickkopf 1 like, Dickkopf homolog 1, Dickkopf related protein 1, Dickkopf-1, Dickkopf-related protein 1, Dickkopf-related protein 1 Dickkopf 1, DKK 1, DKK1, DKK-1, hDkk 1, hDkk1, hDkk-1, SK, Xenopus laevis, ATGP0269-10ug, ATGP0269-20ug, ATGP0269-50ug, ATGP0269-100ug, ATGP0269-250ug, ATGP0269-500ug, ATGP0269-1mg, ATGP0269-010, ATGP0269-020, ATGP0269-050, ATGP0269-100, ATGP0269-250, ATGP0269-500, ATGP0269-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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