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Recombinant human 4-1BB Ligand/TNFSF9 protein

ArtNr NKM-ATGP0308-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMRE GPELSPDDPA GLLDLRQGMF AQLVAQNVLL IDGPLSWYSD PGLAGVSLTG GLSYKEDTKE LVVAKAGVYY VFFQLELRRV VAGEGSGSVS LALHLQPLRS AAGAAALALT VDLPPASSEA RNSAFGFQGR LLHLSAGQRL GVHLHTEARA RHAWQLTQGA TVLGLFRVTP EIPAGLPSPR SE
Citations Lee SW., et al. (2008). Nat Immunol. 9(8):917-26
Sharma RK., et al. (2009). Cancer Res. 69(10):4319-26
NCBI NP_003802
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Tumor necrosis factor ligand superfamily member 9,4-1BB ligand,4-1BBL,receptor 4-1BB ligand,homolog of mouse 4-1BB-L,CD137 ligand,CD137L
Similar products 4-1BBL, TNFSF9, 4 1BBL, CD137L, Tumor necrosis factor ligand superfamily member 9, 4-1BB ligand, 4 1BB L, 4 1BB ligand, Cd137l, Cd157l, Ly63l, homolog of mouse 4 1BB L, homolog of mouse 4 1BBL, ILA ligand (TNF related), receptor 4 1BB ligand, 41BB Ligand, Tumor necrosis factor (ligand) superfamily member 9., ATGP0308-10ug, ATGP0308-20ug, ATGP0308-50ug, ATGP0308-100ug, ATGP0308-250ug, ATGP0308-500ug, ATGP0308-1mg, ATGP0308-10, ATGP0308-20, ATGP0308-50, ATGP0308-100, ATGP0308-250, ATGP0308-500, ATGP0308-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
23.8 kDa (222aa) confirmed by MALDI-TOF
Description
4-1BB ligand is a type 2 transmembrane glycoprotein belonging to the TNF superfamily. 4-1BBL is expressed by activated B cells, macrophages, dendritic cells, activated T cells, neurons and astrocytes. The interaction of 4-1BB with 4-1BBL strongly regulates immunity and has been proposed to preferentially control T cell responses based on studies in various murine models of cancer, infectious disease and autoimmune disease. Recombinant human 4-1BB ligand, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 20% glycerol
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
71-254aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Human TNFRSF9 (CAT# ATGP3303).
Species of Protein
Human
Manufacturer - Search Terms
41BB Ligand, TNFSF9, Tumor necrosis factor ligand superfamily member 9, TNFSF9, 4-1BBL, CD137L, 4-1BB ligand, 4 1BB L, 4 1BB ligand, 4 1BBL, Cd137l, Cd157l, homolog of mouse 4 1BB L, homolog of mouse 4 1BBL, ILA ligand (TNF related), Ly63l, receptor 4 1BB ligand, Tumor necrosis factor (ligand) superfamily member 9., ATGP0308-10ug, ATGP0308-20ug, ATGP0308-50ug, ATGP0308-100ug, ATGP0308-250ug, ATGP0308-500ug, ATGP0308-1mg, ATGP0308-10, ATGP0308-20, ATGP0308-50, ATGP0308-100, ATGP0308-250, ATGP0308-500, ATGP0308-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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