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Recombinant human BMF protein

ArtNr NKM-ATGP0324-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag T7 Epitope
Purity > 90% by SDS-PAGE
Sequence MASMTGGQQM GRGSHMEPSQ CVEELEDDVF QPEDGEPVTQ PGSLLSADLF AQSLLDCPLS RLQLFPLTHC CGPGLRPTSQ EDKATQTLSP ASPSQGVMLP CGVTEEPQRL FYAPAEPKSC VVADPPLPAQ PCFEWRREQE RGRP
Citations Morales AA., et al. (2004). Leukemia. 18(1):41-7
Chen L., et al. (2005). Mol Cell. 17(3):393-403
NCBI NP_001003943
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Bcl2 modifying factor isoform 3,Bcl2 modifying factor,isoform 3,BMF,Bcl2 modifying factor,isoform 3 Bcl 2 modifying factor,FLJ00065.
Similar products BMF, Bcl2 modifying factor, isoform 3, FLJ00065., Bcl2 modifying factor isoform 3, isoform 3 Bcl 2 modifying factor, ATGP0324-10ug, ATGP0324-20ug, ATGP0324-50ug, ATGP0324-100ug, ATGP0324-250ug, ATGP0324-500ug, ATGP0324-1mg, ATGP0324-10, ATGP0324-20, ATGP0324-50, ATGP0324-100, ATGP0324-250, ATGP0324-500, ATGP0324-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
15.6 kDa (144aa) confirmed by MALDI-TOF
Description
Bcl2 modifying factor, also known as BMF belongs to the Bcl2 protein family of apoptosis mediators. Bmf is constitutively expressed in many tissues. This protein contains a single Bcl2 homology domain 3 (BH3), and has been shown to bind Bcl2 proteins and function as an apoptotic activator. Also, BMF is a key molecule for histone deacetylase (HDAC) inhibitors which alters the balance between acetylation and deacetylation, significantly increasing histone acetylation, while strongly inducing apoptosis in a variety of cancer cell types. Recombinant human BMF, fused to T7-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing, 1mM DTT, 10% glycerol
Antigen Species
Human
Gene Category
Cancer
Domain
1-129aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
BMF, Bcl2 modifying factor isoform 3, Bcl2 modifying factor, isoform 3, BMF, Bcl2 modifying factor, isoform 3 Bcl 2 modifying factor, FLJ00065., ATGP0324-10ug, ATGP0324-20ug, ATGP0324-50ug, ATGP0324-100ug, ATGP0324-250ug, ATGP0324-500ug, ATGP0324-1mg, ATGP0324-10, ATGP0324-20, ATGP0324-50, ATGP0324-100, ATGP0324-250, ATGP0324-500, ATGP0324-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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