Recombinant human PRL-3/PTP4A3 protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Protein tyrosine phosphatase type IVA 3 (PRL-3), as known as PTP4A3, belongs to a small class of prenylated protein tyrosine phosphatases (PTPs) that remove phosphate modifications from tyrosine residues on proteins. This protein enhances cell proliferation, cell motility and invasive activity. High levels of PRL-3 expression are associated with tumorigenesis and metastasis, thus it is overexpressed in metastatic colorectal, ovarian, liver and skin cancers. Recombinant human PRL-3, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2mM EDTA, 1mM DTT, 10% glycerol

Enzymes & Proteases

< 1 EU per 1ug of protein (determined by LAL method)

PRL3, PTP4A3, Protein tyrosine phosphatase type IVA 3, PTP4A3, PRL3, Protein tyrosine phosphatase type IVA 3 Potentially prenylated protein tyrosine phosphatase, PRL 3, PRL R, PRLR, Protein tyrosine phosphatase 4a3, PTP 4A3, Protein Tyrosine Phosphatase Type IVA Member 3, ATGP0398-10ug, ATGP0398-20ug, ATGP0398-50ug, ATGP0398-100ug, ATGP0398-250ug, ATGP0398-500ug, ATGP0398-1mg, ATGP0398-10, ATGP0398-20, ATGP0398-50, ATGP0398-100, ATGP0398-250, ATGP0398-500, ATGP0398-1