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Recombinant human Galectin-3/LGALS3 protein

ArtNr NKM-ATGP0414-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MADNFSLHDA LSGSGNPNPQ GWPGAWGNQP AGAGGYPGAS YPGAYPGQAP PGAYPGQAPP GAYPGAPGAY PGAPAPGVYP GPPSGPGAYP SSGQPSATGA YPATGPYGAP AGPLIVPYNL PLPGGVVPRM LITILGTVKP NANRIALDFQ RGNDVAFHFN PRFNENNRRV IVCNTKLDNN WGREERQSVF PFESGKPFKI QVLVEPDHFK
Citations Barondes SH., et al. (1994) J Biol Chem. 269(33):20807-10.
Kadrofske MM., et al. (1998) Arch Biochem Biophys. 349(1):7-20.
Campanero-Rhodes, M.A, et al. Exploration of Galectin Ligands Displayed on Gram-Negative Respiratory Bacterial Pathogens with Different Cell Surface Architectures. (Biomolecules. 2021){https://pubmed.ncbi.nlm.nih.gov/33919637/}
NCBI NP_002297.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Gal-3,35 kDa lectin,Carbohydrate-binding protein 35,CBP 35,Galactose-specific lectin 3,Galactoside-binding protein,GALBP,IgE-binding protein,L-31,Laminin-binding protein,Lectin L-29,Mac-2 antigen,MAC2,Advanced glycation end-product receptor 3,GALIG
Similar products Galectin-3, LGALS2, LGALS3, 35 kDa lectin, Galactose-specific lectin 3, Galactoside-binding protein, IgE-binding protein, Laminin-binding protein, Lectin L-29, L-34 galactoside-binding lectin, Macrophage galactose-specific lectin, GALBP, GAL3, GBP, CBP35, GALIG, L31, included, Carbohydrate binding protein 35, Galectin3, IgE binding protein, L 31, L 34, Lectin, galactose binding, soluble 3, MAC 2 antigen, Mac-2, Galectin 3 internal gene, MAC2., MGC105387., ATGP0414-10ug, ATGP0414-20ug, ATGP0414-50ug, ATGP0414-100ug, ATGP0414-250ug, ATGP0414-500ug, ATGP0414-1mg, ATGP0414-10, ATGP0414-20, ATGP0414-50, ATGP0414-100, ATGP0414-250, ATGP0414-500, ATGP0414-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
28.3 kDa (270aa) confirmed by MALDI-TOF
Description
Galectin-3 is a member of the family of animal lectins, which selectively binds beta-galactoside residues. This protein is secreted from cells by ectocytosis, which is independent of the classical secretory pathway through the endoplasmic reticulum/Golgi network. Galectin-3 has been associated with the inhibition of apoptosis and the progression of cancer. It is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. Recombinant Galectin-3 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl
Antigen Species
Human
Gene Category
Differentiation & Regeneration
Domain
1-250aa
Bioactivity Comment Only
The ED50 for this effect is less or equal to 15ug/ml. Measured by its ability to agglutinate human red blood cells.
Species of Protein
Human
Manufacturer - Search Terms
Galectin3, CBP35, GAL3, GALBP, GALIG, LGALS2, MAC2., 35 kDa lectin, Carbohydrate binding protein 35, Galactose-specific lectin 3, Galactoside-binding protein, Galectin 3 internal gene, included, Galectin-3, Galectin3, GBP, IgE binding protein, IgE-binding protein, L 31, L 34, L-34 galactoside-binding lectin, L31, LGALS3, Laminin-binding protein, Lectin L-29, MAC 2 antigen, Lectin, galactose binding, soluble 3, Mac-2, Macrophage galactose-specific lectin, MGC105387., ATGP0414-10ug, ATGP0414-20ug, ATGP0414-50ug, ATGP0414-100ug, ATGP0414-250ug, ATGP0414-500ug, ATGP0414-1mg, ATGP0414-10, ATGP0414-20, ATGP0414-50, ATGP0414-100, ATGP0414-250, ATGP0414-500, ATGP0414-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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