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Recombinant human PDCD6IP protein

ArtNr NKM-ATGP0482-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MATFISVQLK KTSEVDLAKP LVKFIQQTYP SGGEEQAQYC RAAEELSKLR RAAVGRPLDK HEGALETLLR YYDQICSIEP KFPFSENQIC LTFTWKDAFD KGSLFGGSVK LALASLGYEK SCVLFNCAAL ASQIAAEQNL DNDEGLKIAA KHYQFASGAF LHIKETVLSA LSREPTVDIS PDTVGTLSLI MLAQAQEVFF LKATRDKMKD
Citations Morita E., et al. (2007) EMBO J. 26(19):4215-27.
Katoh K., et al. (2004) Arch Biochem Biophys. 421(1):159-65.
NCBI NP_037506.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Programmed cell death 6 interacting protein,PDCD6-interacting protein,ALG-2 interacting protein X,ALG-2-interacting protein 1,Alix,AIP1,Hp95
Similar products Alix, ATGP0482-10ug, ATGP0482-20ug, ATGP0482-50ug, ATGP0482-100ug, ATGP0482-250ug, ATGP0482-500ug, ATGP0482-1mg, ATGP0482-10, ATGP0482-20, ATGP0482-50, ATGP0482-100, ATGP0482-250, ATGP0482-500, ATGP0482-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
45.8 kDa (412aa) confirmed by MALDI-TOF
Description
Alix, also known as PDCD6IP, is a cytoplasmic protein that interacts with apoptosis-associated proteins (ALG-2 and PDCD6) and with the endocytosis-regulator CIN85. It's involved in concentration and sorting of cargo proteins of the multivesicular body for incorporation into intralumenal vesicles that are generated by invagination and scission from the limiting membrane of the endosome. Overexpression of this protein and endophilins results in cytoplasmic vacuolization which may be partly responsible for the protection against cell death. Recombinant PDCD6IP protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT
Antigen Species
Human
Gene Category
Apoptosis
Domain
1-392aa
Species of Protein
Human
Manufacturer - Search Terms
Alix, ATGP0482-10ug, ATGP0482-20ug, ATGP0482-50ug, ATGP0482-100ug, ATGP0482-250ug, ATGP0482-500ug, ATGP0482-1mg, ATGP0482-10, ATGP0482-20, ATGP0482-50, ATGP0482-100, ATGP0482-250, ATGP0482-500, ATGP0482-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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