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Recombinant human LTA/TNF-beta protein

ArtNr NKM-ATGP0517-250ug
Hersteller NKMAX
Menge 250 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MLPGVGLTPS AAQTARQHPK MHLAHSTLKP AAHLIGDPSK QNSLLWRANT DRAFLQDGFS LSNNSLLVPT SGIYFVYSQV VFSGKAYSPK ATSSPLYLAH EVQLFSSQYP FHVPLLSSQK MVYPGLQEPW LHSMYHGAAF QLTQGDQLST HTDGIPHLVL SPSTVFFGAF AL
Citations Messer G, et al. (1991) J Exp Med. 173(1):209-19
Banner DW, et al. (1993) Cell. 73(3):431-45.
NCBI NP_001153212
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Lymphotoxin-alpha,LT-alpha,TNF-beta,Tumor necrosis factor ligand superfamily member 1,TNFB,TNFSF1,TNF superfamily,member 1
Similar products LTA, TNF B, TNF b, Tumor necrosis factor ligand superfamily member 1, TNFB, TNFSF1, TNFbeta, LT, DIF, Differentiation inducing factor, Hemorrhagic factor, LT alpha, LTalpha, Lymphotoxin alpha, Lymphotoxin alpha (TNF superfamily, member 1), Natural killer cytotoxic factor, Necrosin, NKCF, TNF superfamily member 1, TNFSF 1, Tumor necrosis factor beta, Tumor necrosis factor superfamily member 1, Coley's toxin, Lymphotoxin a1, CLTalpha, OTTHuMP00000037612, OTTHuMP00000037613, ATGP0517-10ug, ATGP0517-20ug, ATGP0517-50ug, ATGP0517-100ug, ATGP0517-250ug, ATGP0517-500ug, ATGP0517-1mg, ATGP0517-10, ATGP0517-20, ATGP0517-50, ATGP0517-100, ATGP0517-250, ATGP0517-500, ATGP0517-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
20.9 kDa (192aa) confirmed by MALDI-TOF
Description
TNF beta, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Recombinant TNF beta protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 0.1M NaCl, 1mM DTT
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
35-205aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured in a cytotoxicity assay using L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 range ≤ 1ng/ml.
Species of Protein
Human
Manufacturer - Search Terms
Lymphotoxin a1, TNF b, Lymphotoxin alpha, CLTalpha, Coley's toxin, DIF, Differentiation inducing factor, Hemorrhagic factor, LT, LT alpha, LTA, LTalpha, Lymphotoxin alpha, Lymphotoxin alpha (TNF superfamily, member 1), Natural killer cytotoxic factor, Necrosin, NKCF, OTTHuMP00000037612, OTTHuMP00000037613, TNF B, TNF superfamily member 1, TNFB, TNFbeta, TNFSF 1, TNFSF1, Tumor necrosis factor beta, Tumor necrosis factor ligand superfamily member 1, Tumor necrosis factor superfamily member 1, Lymphotoxin alpha, ATGP0517-10ug, ATGP0517-20ug, ATGP0517-50ug, ATGP0517-100ug, ATGP0517-250ug, ATGP0517-500ug, ATGP0517-1mg, ATGP0517-10, ATGP0517-20, ATGP0517-50, ATGP0517-100, ATGP0517-250, ATGP0517-500, ATGP0517-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 250 ug
Lieferbar: In stock
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