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Recombinant human FHIT protein

Recombinant human FHIT protein

ArtNr	NKM-ATGP0563-100ug
Hersteller	NKMAX
Menge	100 ug
Quantity options	100 ug 20 ug 500 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid
Applikationen	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Konjugat/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	MSFRFGQHLI KPSVVFLKTE LSFALVNRKP VVPGHVLVCP LRPVERFHDL RPDEVADLFQ TTQRVGTVVE KHFHGTSLTF SMQDGPEAGQ TVKHVHVHVL PRKAGDFHRN DSIYEELQKH DKEDFPASWR SEEEMAAEAA ALRVYFQ<LEH HHHHH>
Citations	Kmiec Z., et al. (2009) J Physiol Pharmacol. 60(4):63-70. Ahmad F., et al. (2010) J Cancer Res Clin Oncol. 136(3):333-50. Kawaguchi M, et al. Synthesis of Fluorescent Probes Targeting Tumor-Suppressor Protein FHIT and Identification of Apoptosis-Inducing FHIT Inhibitors. (J Med Chem. 2021){https://pubmed.ncbi.nlm.nih.gov/34160227/}
NCBI	NP_002003
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Bis(5'-adenosyl)-triphosphatase,AP3A hydrolase,AP3Aase,Adenosine 5'-monophosphoramidase FHIT,Adenylylsulfatase,Adenylylsulfate-ammonia adenylyltransferase,Diadenosine 5',5'''-P1,P3-triphosphate hydrolase,Dinucleosidetriphosphatase,Fragile histidine triad protein,FRA3B
Similar products	FHIT, AP3Aase, FRA3B, Fragile histidine triad, Dinucleosidetriphosphatase, Fragile histidine triad protein, AP3A hydrolase fragile site 3p14.2, Bis 5' adenosyl triphosphatase, FRA 3B, Fragile histidine triad gene, Tumor suppressor protein., Diadenosine 5' 5''' P1 P3 triphosphate hydrolase, Bis (5'-adenosyl)-triphosphatase, Fragile histidine triad protein AP3A hydrolase, ATGP0563-10ug, ATGP0563-20ug, ATGP0563-50ug, ATGP0563-100ug, ATGP0563-250ug, ATGP0563-500ug, ATGP0563-1mg, ATGP0563-10, ATGP0563-20, ATGP0563-50, ATGP0563-100, ATGP0563-250, ATGP0563-500, ATGP0563-1
Lieferbar
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	17.9 kDa (155aa) confirmed by MALDI-TOF
Description	FHIT (fragile histidine triad) is an enzyme that cleaves adenosine 5' PPP 5' A to yield AMP and ADP. FHIT gene encompasses the common fragile site FRA3B on chromosome 3. Alterations and deletions of the FHIT gene are strongly linked to the genesis and establishment of human tumors of the lung, cervix, breast, colon, stomach and pancreas. In normal cells, FHIT may act as a tumor suppressor. This protein physically associates with ubiquitin conjugating enzyme 9. Recombinant human FHIT, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species	Human
Gene Category	Enzymes & Proteases
Domain	1-147aa
Species of Protein	Human
Manufacturer - Search Terms	FHIT, Fragile histidine triad protein, Bis (5'-adenosyl)-triphosphatase, AP3Aase, Fragile histidine triad protein AP3A hydrolase, AP3A hydrolase fragile site 3p14.2, Bis 5' adenosyl triphosphatase, Diadenosine 5' 5''' P1 P3 triphosphate hydrolase, Dinucleosidetriphosphatase, FRA 3B, FRA3B, Fragile histidine triad, Fragile histidine triad gene, Fragile histidine triad protein, Tumor suppressor protein., ATGP0563-10ug, ATGP0563-20ug, ATGP0563-50ug, ATGP0563-100ug, ATGP0563-250ug, ATGP0563-500ug, ATGP0563-1mg, ATGP0563-10, ATGP0563-20, ATGP0563-50, ATGP0563-100, ATGP0563-250, ATGP0563-500, ATGP0563-1
Manufacturer - Alternative Names	Bis(5'-adenosyl)-triphosphatase, AP3A hydrolase, AP3Aase, Adenosine 5'-monophosphoramidase FHIT, Adenylylsulfatase, Adenylylsulfate-ammonia adenylyltransferase, Diadenosine 5', 5'''-P1, P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Fragile histidine triad protein, FRA3B

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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NKM-ATGP0563-100ug-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 31.07.2025

Express-Lieferung: 3 Tage sparen

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