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Recombinant human Tau 352 (0N3R)/MAPT protein

ArtNr NKM-ATGP0646-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MAEPRQEFEV MEDHAGTYGL GDRKDQGGYT MHQDQEGDTD AGLKAEEAGI GDTPSLEDEA AGHVTQARMV SKSKDGTGSD DKKAKGADGK TKIATPRGAA PPGQKGQANA TRIPAKTPPA PKTPPSSGEP PKSGDRSGYS SPGSPGTPGS RSRTPSLPTP PTREPKKVAV VRTPPKSPSS AKSRLQTAPV PMPDLKNVKS KIGSTENLKH
Citations Jack CR Jr., et al. (2010) Lancet Neurol. 9(1):119-28.
Buescher JL., et al. (2010) J Biol Chem. 285(11):7957-63.
NCBI NP_058525
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias microtubule-associated protein isoform 4,fetal tau,Neurofibrillary tangle protein,Paired helical filament-tau,PHF-tau,G protein beta1/gamma2 subunit-interacting factor 1,protein phosphatase 1 regulatory subunit 103,MTBT1,PPND,FTDP-17,TAU,MSTD,MTBT2,FLJ31424,MGC138549,PPP1R103,tau-40,DDPAC,MAPTL
Similar products Tau, MAPTL, MTBT1, Microtubule-associated protein tau, DDPAC, FTDP-17, MSTD, MTBT2, PPND, TAu, ATGP0646-10ug, ATGP0646-20ug, ATGP0646-50ug, ATGP0646-100ug, ATGP0646-250ug, ATGP0646-500ug, ATGP0646-1mg, ATGP0646-10, ATGP0646-20, ATGP0646-50, ATGP0646-100, ATGP0646-250, ATGP0646-500, ATGP0646-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
38.9 kDa (372aa) confirmed by MALDI-TOF (Real Molecular weight on SDS-PAGE will be shift up)
Description
MAPT, also known as TAu, is a neuronal microtubule associated protein found predominantly on axons. The function of this protein is to promote tubulin polymerisation and stabilise microtubules, but it also serves to link certain signalling pathways to the cytoskeleton. MAPT, in its hyperphosphorylated form, is the major component of paired helical filaments (PHF) and neurofibrillary lesions in Alzheimer's disease (AD) brain. Recombinant human MAPT protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Concentration
0.5mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M Nacl, 1mM DTT, 10% glycerol
Antigen Species
Human
Gene Category
Neuroscience
Domain
1-352aa
Species of Protein
Human
Manufacturer - Search Terms
Tau, Microtubule-associated protein tau, TAu, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, Microtubule-associated protein tau, ATGP0646-10ug, ATGP0646-20ug, ATGP0646-50ug, ATGP0646-100ug, ATGP0646-250ug, ATGP0646-500ug, ATGP0646-1mg, ATGP0646-10, ATGP0646-20, ATGP0646-50, ATGP0646-100, ATGP0646-250, ATGP0646-500, ATGP0646-1
Manufacturer - Alternative Names
microtubule-associated protein isoform 4, fetal tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, G protein beta1/gamma2 subunit-interacting factor 1, protein phosphatase 1 regulatory subunit 103, MTBT1, PPND, FTDP-17, TAU, MSTD, MTBT2, FLJ31424, MGC138549, PPP1R103, tau-40, DDPAC, MAPTL

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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