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Recombinant human Galectin-8/LGALS8 protein

ArtNr NKM-ATGP0688-250ug
Hersteller NKMAX
Menge 250 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MMLSLNNLQN IIYNPVIPFV GTIPDQLDPG TLIVIRGHVP SDADRFQVDL QNGSSMKPRA DVAFHFNPRF KRAGCIVCNT LINEKWGREE ITYDTPFKRE KSFEIVIMVL KDKFQVAVNG KHTLLYGHRI GPEKIDTLGI YGKVNIHSIG FSFSSDLQST QASSLELTEI SRENVPKSGT PQLRLPFAAR LNTPMGPGRT VVVKGEVNAN
Citations Kobayashi T., et al. (2010) Leukemia. 24(4):843-50.
Streetly MJ., et al. (2010) Blood. 115(19):3939-48.
Suzuki O et al., Sialylation by B-galactoside a-2,6-sialyltransferase and N-glycans regulate cell adhesion and invasion in human anaplastic large cell lymphoma. (Int J Oncol. 2015)
Campanero-Rhodes, M.A, et al. Exploration of Galectin Ligands Displayed on Gram-Negative Respiratory Bacterial Pathogens with Different Cell Surface Architectures. (Biomolecules. 2021)
NCBI NP_963837
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Prostate carcinoma tumor antigen 1,Po66-CBP,Po66 carbohydrate-binding protein,PCTA1,Galectin-8,Gal-8
Lieferbar
Manufacturer - Type
Proteins
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Category
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
37.9 kDa (337aa) confirmed by MALDI-TOF
Description
LGALS8, also known as prostate-specific membrane antigen (PCTA1), is an additional prostate-specific antigen that is overexpressed only in malignant tumors and therefore is a more specific identifier of malignancies. It is a member of the galectin gene family which mediates both cell-cell and cell matrix interactions in a manner similar to the selectin subgroup of C-type lectins. Recombinant human LGALS8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M Nacl, 1mM DTT, 10% glycerol
Antigen Species
Human
Gene Category
Cancer
Domain
1-317aa
Bioactivity Comment Only
Measured by its ability to agglutinate human red blood cells. The ED50 range ≤ 10 ug/ml.
Species of Protein
Human
Manufacturer - Search Terms
Galectin8, Galectin-8, Gal-8, PCTA1, Po66-CBP, Prostate carcinoma tumor antigen 1, Galectin-8, ATGP0688-10ug, ATGP0688-20ug, ATGP0688-50ug, ATGP0688-100ug, ATGP0688-250ug, ATGP0688-500ug, ATGP0688-1mg, ATGP0688-10, ATGP0688-20, ATGP0688-50, ATGP0688-100, ATGP0688-250, ATGP0688-500, ATGP0688-1
Manufacturer - Similar Names
Galectin8, Galectin-8, Gal-8, PCTA1, Po66-CBP, Prostate carcinoma tumor antigen 1, Galectin-8, ATGP0688-10ug, ATGP0688-20ug, ATGP0688-50ug, ATGP0688-100ug, ATGP0688-250ug, ATGP0688-500ug, ATGP0688-1mg, ATGP0688-10, ATGP0688-20, ATGP0688-50, ATGP0688-100, ATGP0688-250, ATGP0688-500, ATGP0688-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 250 ug
Lieferbar: In stock
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