Recombinant human PRL-2/PTP4A2 protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Protein tyrosine phosphatase type IVA 2 isoform 1, also known as PTP4A2, belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTP4A2 is localized to the early endosome that play regulatory roles in a variety of cellular processes. This protein was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Recombinant human PTP4A2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Cancer

Human

Protein tyrosine phosphatase type IVA 2 isoform 1, HH13, HH7-2, Hu-PP-1, OV-1, PRL-2, PRL2, ptp-IV1a, ptp-IV1b, PTP4A, PTPCAAX2, EC 3.1.3.48, HH13, HH7 2, HuPP 1, HuPP1, OV 1, OV1, PRL 2, PRL2, Protein tyrosine phosphatase 4a2, Protein tyrosine phosphatase of regenerating liver 2, Protein tyrosine phosphatase type IVA member 2 isoform 1, PTP (CAAXII), ptp IV1a, ptp IV1b, PTP4A, PTPCAAX2