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Recombinant human DIRAS1 protein

ArtNr NKM-ATGP0724-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MPEQSNDYRV VVFGAGGVGK SSLVLRFVKG TFRDTYIPTI EDTYRQVISC DKSVCTLQIT DTTGSHQFPA MQRLSISKGH AFILVFSVTS KQSLEELGPI YKLIVQIKGS VEDIPVMLVG NKCDETQREV DTREAQAVAQ EWKCAFMETS AKMNYNVKEL FQELLTLETR RNMSLNIDGK RSGKQKRTDR VKGKC
Citations Ellis CA., et al. (2002) Proc Natl Acad Sci u S A. 99(15):9876-81.
Kontani K., et al. (2002) J Biol Chem. 277(43):41070-8.
NCBI NP_660156.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias GTP-binding protein Di-Ras1.,Di-Ras1,FLJ42681,GBTS1,RIG,GTP-binding protein Di-Ras1.
Similar products DIRAS1, Di-Ras1, FLJ42681, GBTS1, RIG, GTP-binding protein Di-Ras1., ATGP0724-10ug, ATGP0724-20ug, ATGP0724-50ug, ATGP0724-100ug, ATGP0724-250ug, ATGP0724-500ug, ATGP0724-1mg, ATGP0724-10, ATGP0724-20, ATGP0724-50, ATGP0724-100, ATGP0724-250, ATGP0724-500, ATGP0724-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
24.1 kDa (215aa) confirmed by MALDI-TOF
Description
DIRAS1 belongs to a distinct branch of the functionally diverse Ras superfamily of monomeric GTPases. Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis. DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. Recombinant human DIRAS1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT, 0.1M NaCl, 1mM EDTA
Antigen Species
Human
Gene Category
Cancer
Domain
1-195aa
Species of Protein
Human
Manufacturer - Search Terms
DIRAS1, GTP-binding protein Di-Ras1., Di-Ras1, FLJ42681, GBTS1, RIG, GTP-binding protein Di-Ras1., ATGP0724-10ug, ATGP0724-20ug, ATGP0724-50ug, ATGP0724-100ug, ATGP0724-250ug, ATGP0724-500ug, ATGP0724-1mg, ATGP0724-10, ATGP0724-20, ATGP0724-50, ATGP0724-100, ATGP0724-250, ATGP0724-500, ATGP0724-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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