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Recombinant human Glyoxalase II protein

Recombinant human Glyoxalase II protein

ArtNr	NKM-ATGP0808-50ug
Hersteller	NKMAX
Menge	50 ug
Quantity options	10 ug 250 ug 50 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid
Applikationen	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Konjugat/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MGSHMKVEVL PALTDNYMYL VIDDETKEAA IVDPVQPQKV VDAARKHGVK LTTVLTTHHH WDHAGGNEKL VKLESGLKVY GGDDRIGALT HKITHLSTLQ VGSLNVKCLA TPCHTSGHIC YFVSKPGGSE PPAVFTGDTL FVAGCGKFYE GTADEMCKAL LEVLGRLPPD TRVYCGHEYT INNLKFARHV EPGNAAIREK LAWAKEKYSI GE
Citations	Vila AJ., et al. (2010) J Inorg Biochem. 104(7):726-31. Crowder MW., et al (2009) Biochemistry. 48(23):5426-34.
NCBI	NP_001035517
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Hydroxyacylglutathione hydrolase,GLO,GLX2,Glyoxalase II,HAGH1
Similar products	HAGH1, Hydroxyacylglutathione hydrolase, Glyoxalase II, GLX2, GLO, ATGP0808-10ug, ATGP0808-20ug, ATGP0808-50ug, ATGP0808-100ug, ATGP0808-250ug, ATGP0808-500ug, ATGP0808-1mg, ATGP0808-10, ATGP0808-20, ATGP0808-50, ATGP0808-100, ATGP0808-250, ATGP0808-500, ATGP0808-1
Lieferbar
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	Enzyme Activity, SDS-PAGE
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	31.4 kDa (284aa) confirmed by MALDI-TOF
Description	HAGH is a member of the glyoxalase family and a thiolesterase which hydrolyses S-lactoyl-glutathione to reduced glutathione and D-lactate. This protein is a detoxifying enzyme of glycolysis byproduct methylglyoxal and a target of p63 and p73 and serves as a pro-survival factor of the p53 family. It exists only as a monomer and binds two zinc ions per subunit. Recombinant human HAGH protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration	0.5mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.5) containing 10% glycerol
Antigen Species	Human
Gene Category	Enzymes & Proteases
Domain	1-260aa
Bioactivity Comment Only	Specific activity is > 500unit/mg, and is defined as the amount of enzyme that reduce 1.0 umole of 5, 5 -Dithiobis(2-nitrobenzoic acid) (DTNB) with reduced glutathione per minute at pH 7.5 at 37C.
Species of Protein	Human
Manufacturer - Search Terms	Glyoxalase II, Hydroxyacylglutathione hydrolase, GLO, GLX2, Glyoxalase II, HAGH1, ATGP0808-10ug, ATGP0808-20ug, ATGP0808-50ug, ATGP0808-100ug, ATGP0808-250ug, ATGP0808-500ug, ATGP0808-1mg, ATGP0808-10, ATGP0808-20, ATGP0808-50, ATGP0808-100, ATGP0808-250, ATGP0808-500, ATGP0808-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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NKM-ATGP0808-50ug-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 02.10.2025

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