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Recombinant human ATF3 protein

ArtNr NKM-ATGP1127-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag Untagged
Purity > 90% by SDS-PAGE
Sequence MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S
Citations Lv D., et al. (2011) IuBMB Life. 63(1):62-9.
Chen BP., et al. (1994) J Biol Chem 269 (22): 15819-26.
Sato A, et al. Role of activating transcription factor 3 protein ATF3 in necrosis and apoptosis induced by 5-fluoro-2-deoxyuridine. (FEBS J. 2014){https://pubmed.ncbi.nlm.nih.gov/24529083/}
NCBI NP_001665
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Activating transcription factor 3,ATF3deltaZip3,cAMP dependent transcription factor ATF3,Cyclic AMP dependent transcription factor ATF3,Cyclic AMP-dependent transcription factor ATF-3
Similar products ATF3, Cyclic AMP-dependent transcription factor ATF-3, Activating transcription factor 3, ATF3deltaZip2, ATF3deltaZip2c, ATF3deltaZip3, cAMP dependent transcription factor ATF3, Cyclic AMP dependent transcription factor ATF3, ATGP1127-10ug, ATGP1127-20ug, ATGP1127-50ug, ATGP1127-100ug, ATGP1127-250ug, ATGP1127-500ug, ATGP1127-1mg, ATGP1127-10, ATGP1127-20, ATGP1127-50, ATGP1127-100, ATGP1127-250, ATGP1127-500, ATGP1127-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
20.6 kDa (181aa)
Description
ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-181aa
Species of Protein
Human
Manufacturer - Search Terms
ATF3, Activating transcription factor 3, ATF3deltaZip2, ATF3deltaZip2c, ATF3deltaZip3, cAMP dependent transcription factor ATF3, Cyclic AMP dependent transcription factor ATF3, Cyclic AMP-dependent transcription factor ATF-3, ATGP1127-10ug, ATGP1127-20ug, ATGP1127-50ug, ATGP1127-100ug, ATGP1127-250ug, ATGP1127-500ug, ATGP1127-1mg, ATGP1127-10, ATGP1127-20, ATGP1127-50, ATGP1127-100, ATGP1127-250, ATGP1127-500, ATGP1127-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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