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Recombinant human Glutathione Peroxidase 1/GPX1 (U49C) protein

ArtNr NKM-ATGP1273-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MCAARLAAAA AAAQSVYAFS ARPLAGGEPV SLGSLRGKVL LIENVASLCG TTVRDYTQMN ELQRRLGPRG LVVLGFPCNQ FGHQENAKNE EILNSLKYVR PGGGFEPNFM LFEKCEVNGA GAHPLFAFLR EALPAPSDDA TALMTDPKLI TWSPVCRNDV AWNFEKFLVG PDGVPLRRYS RRFQTIDIEP DIEALLSQGP SCA
Citations Ichimura Y., et al. (2004) J urol.172 (2):728-32.
Li S, Yan T, et al. (2000) Cancer Res.Jul 60(14):3927-39.
NCBI NP_000572.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Glutathione peroxidase 1,GSHPX1,Selenoprotein GPX1,GPx-1
Similar products Glutathione Peroxidase1, GPX1(U49C), ATGP1273-10ug, ATGP1273-20ug, ATGP1273-50ug, ATGP1273-100ug, ATGP1273-250ug, ATGP1273-500ug, ATGP1273-1mg, ATGP1273-10, ATGP1273-20, ATGP1273-50, ATGP1273-100, ATGP1273-250, ATGP1273-500, ATGP1273-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
24.2 kDa (223aa) confirmed by MALDI-TOF
Description
GPX1 (Glutathione peroxidase 1) belongs to the glutathione peroxidase family, consisting of eight known glutathione peroxidases (Gpx1-8) in humans. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. The GPX1 is part of the enzymatic antioxidant defence, preventing oxidative damage to DNA, proteins and lipids by detoxifying hydrogen and lipid peroxides that may contribute to prostate cancer development. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. Recombinant human GPX1 (u49C) protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 30% glycerol, 100mM NaCl
Antigen Species
Human
Gene Category
Redox Proteins
Domain
1-203aa
Species of Protein
Human
Manufacturer - Search Terms
Glutathione Peroxidase1, GPX1(U49C), ATGP1273-10ug, ATGP1273-20ug, ATGP1273-50ug, ATGP1273-100ug, ATGP1273-250ug, ATGP1273-500ug, ATGP1273-1mg, ATGP1273-10, ATGP1273-20, ATGP1273-50, ATGP1273-100, ATGP1273-250, ATGP1273-500, ATGP1273-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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