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Recombinant human p38 alpha/MAPK14 protein

ArtNr NKM-ATGP1300-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGS>MSQERPT FYRQELNKTI WEVPERYQNL SPVGSGAYGS VCAAFDTKTG LRVAVKKLSR PFQSIIHAKR TYRELRLLKH MKHENVIGLL DVFTPARSLE EFNDVYLVTH LMGADLNNIV KCQKLTDDHV QFLIYQILRG LKYIHSADII HRDLKPSNLA VNEDCELKIL DFGLARHTDD EMTGYVATRW YRAPEIMLNW MHYNQTVDIW
Citations Beardmore VA, et al. (2005) Mol Cell Biol. 25(23):10454-64.
Chen, Z, et al (2001) J. Biol. Chem. (united States). 276 (19): 16070-5
NCBI NP_620581.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Mitogen-activated protein kinase 14,CSBP,CSBP1,CSBP2,CSPB1,EXIP,Mxi2,p38,p38ALPHA,PRKM14,PRKM15,RK,SAPK2A
Similar products MAPK14, p38, Mitogen-activated protein kinase 14, RK, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, SAPK2A, p38ALPHA, p38 a, ATGP1300-10ug, ATGP1300-20ug, ATGP1300-50ug, ATGP1300-100ug, ATGP1300-250ug, ATGP1300-500ug, ATGP1300-1mg, ATGP1300-10, ATGP1300-20, ATGP1300-50, ATGP1300-100, ATGP1300-250, ATGP1300-500, ATGP1300-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
43.7 kDa (383aa) confirmed by MALDI-TOF
Description
MAPK14 (Mitogen-activated protein kinase 14) is a member of the MAP kinase family. MAPK14 is most closely related to p38 MAP kinases (MAPKs). MAPKs are activated primarily in response to inflammatory cytokines and cellular stress, and inhibitors which target the MAPK14 and MAPK11 have shown potential for the treatment of inflammatory disease. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress-related transcription and cell cycle regulation, as well as in genotoxic stress response. Recombinant human MAPK14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 100mM NaCl
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-360aa
Species of Protein
Human
Manufacturer - Search Terms
p38 a, MAPK14, Mitogen-activated protein kinase 14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, p38, p38ALPHA, PRKM14, PRKM15, RK, SAPK2A, ATGP1300-10ug, ATGP1300-20ug, ATGP1300-50ug, ATGP1300-100ug, ATGP1300-250ug, ATGP1300-500ug, ATGP1300-1mg, ATGP1300-10, ATGP1300-20, ATGP1300-50, ATGP1300-100, ATGP1300-250, ATGP1300-500, ATGP1300-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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