Recombinant human Histone Deacetylase 8/HDAC8 protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

HDAC8, also known as histone deacetylase 8, belongs to class 1 of the histone deacetylase/acuc/apha family. This protein is biologically involved in skull morphogenesis and metabolic control of the ERR-alpha/PGC1-alpha transcriptional complex. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Recombinant human HDAC8 protein, fused to His-tag at C-terminus, was expressed in Sf9 insect cell and purified by using conventional chromatography.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Epigenomics (Transcription & Translation)

<1 EU per 1ug of protein (determined by LAL method)

Histone Deacetylase8, Histone deacetylase 8, CDA07, HD8, HDACL1, RPD3, ATGP1329-10ug, ATGP1329-20ug, ATGP1329-50ug, ATGP1329-100ug, ATGP1329-250ug, ATGP1329-500ug, ATGP1329-1mg, ATGP1329-10, ATGP1329-20, ATGP1329-50, ATGP1329-100, ATGP1329-250, ATGP1329-500, ATGP1329-1