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Recombinant human GMP synthase/GMPS protein

ArtNr NKM-ATGP1403-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGSH>MALCNG DSKLENAGGD LKDGHHHYEG AVVILDAGAQ YGKVIDRRVR ELFVQSEIFP LETPAFAIKE QGFRAIIISG GPNSVYAEDA PWFDPAIFTI GKPVLGICYG MQMMNKVFGG TVHKKSVRED GVFNISVDNT CSLFRGLQKE EVVLLTHGDS VDKVADGFKV VARSGNIVAG IANESKKLYG AQFHPEVGLT ENGKVILKNF
Citations Hirst M., et al. (1994) J Biol Chem. 269:23830-23837.
Nakamura J., et al. (1995) J Biol Chem. 270:23450-23455.
NCBI NP_003866
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias GMP synthase [glutamine-hydrolyzing],Glutamine amidotransferase,guanine monophosphate synthetase
Similar products GMPS, guanine monophosphate synthetase, Glutamine amidotransferase, GMP synthase [glutamine-hydrolyzing], ATGP1403-10ug, ATGP1403-20ug, ATGP1403-50ug, ATGP1403-100ug, ATGP1403-250ug, ATGP1403-500ug, ATGP1403-1mg, ATGP1403-10, ATGP1403-20, ATGP1403-50, ATGP1403-100, ATGP1403-250, ATGP1403-500, ATGP1403-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
79.2 kDa (717aa)
Description
GMP synthase, also known as GMPS, is involved in purine biosynthesis. Existing as a homodimer, GMPS catalyzes the last step in the GMP synthesis pathway, namely the ATP-dependent amination of XMP to GMP. GMPS contains one GMP-binding domain and one glutamine amidotransferase type-1 domain through which it conveys its catalytic activity. Chromosomal translocations involving the gene encoding GMPS are associated with acute myeloid leukemias, suggesting a possible role for GMPS in carcinogenesis. Recombinant human GMPS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl
Antigen Species
Human
Gene Category
Metabolism
Domain
1-693aa
Species of Protein
Human
Manufacturer - Search Terms
GMPS, GMP synthase [glutamine-hydrolyzing], Glutamine amidotransferase, guanine monophosphate synthetase, ATGP1403-10ug, ATGP1403-20ug, ATGP1403-50ug, ATGP1403-100ug, ATGP1403-250ug, ATGP1403-500ug, ATGP1403-1mg, ATGP1403-10, ATGP1403-20, ATGP1403-50, ATGP1403-100, ATGP1403-250, ATGP1403-500, ATGP1403-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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