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Recombinant human NEIL2 protein

ArtNr NKM-ATGP1526-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSHMPEGPL VRKFHHLVSP FVGQQVVKTG GSSKKLQPAS LQSLWLQDTQ VHGKKLFLRF DLDEEMGPPG SSPTPEPPQK EVQKEGAADP KQVGEPSGQK TLDGSSRSAE LVPQGEDDSE YLERDAPAGD AGRWLRVSFG LFGSVWVNDF SRAKKANKRG DWRDPSPRLV LHFGGGGFLA FYNCQLSWSS SPVVTPTCDI LSEKFHRGQA LE
Citations Hazra TK., et al. (2002) J Biol Chem. 277(34):30417-20.
Das D., et al. (2007) J Biol Chem. 282(39):28474-84.
NCBI NP_659480
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Endonuclease 8-like 2,NEH2,NEI2,Nei-like protein 2
Similar products NEIL2, Endonuclease 8-like 2, Nei-like protein 2, NEH2, NEI2, ATGP1526-10ug, ATGP1526-20ug, ATGP1526-50ug, ATGP1526-100ug, ATGP1526-250ug, ATGP1526-500ug, ATGP1526-1mg, ATGP1526-10, ATGP1526-20, ATGP1526-50, ATGP1526-100, ATGP1526-250, ATGP1526-500, ATGP1526-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
39.4 kDa (356aa) confirmed by MALDI-TOF
Description
Endonuclease 8-like 2, also known as NEIL2, belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. It has negligible or undetectable activity with 8-oxoguanine, thymine glycol, 2-hydroxyadenine, hypoxanthine, and xanthine. Recombinant human NEIL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
Antigen Species
Human
Gene Category
Epigenomics (Transcription & Translation)
Domain
1-332aa
Species of Protein
Human
Manufacturer - Search Terms
NEIL2, Endonuclease 8-like 2, NEH2, NEI2, Nei-like protein 2, ATGP1526-10ug, ATGP1526-20ug, ATGP1526-50ug, ATGP1526-100ug, ATGP1526-250ug, ATGP1526-500ug, ATGP1526-1mg, ATGP1526-10, ATGP1526-20, ATGP1526-50, ATGP1526-100, ATGP1526-250, ATGP1526-500, ATGP1526-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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