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Recombinant human MYL12B protein

ArtNr NKM-ATGP1577-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGSH>MSSKKA KTKTTKKRPQ RATSNVFAMF DQSQIQEFKE AFNMIDQNRD GFIDKEDLHD MLASLGKNPT DAYLDAMMNE APGPINFTMF LTMFGEKLNG TDPEDVIRNA FACFDEEATG TIQEDYLREL LTTMGDRFTD EEVDELYREA PIDKKGNFNY IEFTRILKHG AKDKDD
Citations Kumar C C., et al. (1989) Biochemistry. 28:4027-4035.
Kolodney M S., et al. (1999) J Physiol. 515: 87-92.
NCBI NP_001138417
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Myosin light chain 12B regulatory,Myosin,light chain 12B regulatory,MLC-B,MRLC2
Similar products MYL12B, MRLC2, MLC-B, Myosin, Myosin light chain 12B regulatory, light chain 12B regulatory, ATGP1577-10ug, ATGP1577-20ug, ATGP1577-50ug, ATGP1577-100ug, ATGP1577-250ug, ATGP1577-500ug, ATGP1577-1mg, ATGP1577-10, ATGP1577-20, ATGP1577-50, ATGP1577-100, ATGP1577-250, ATGP1577-500, ATGP1577-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
22.3 kDa (196aa) confirmed by MALDI-TOF
Description
Myosin, light chain 12B, regulatory, also known as MYL12B, is a hexameric ATPase cellular motor protein. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. MYL12B regulates contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases Actin-activated myosin ATPase activity, thereby regulating contractile activity. Recombinant human MYL12B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 2mM DTT
Antigen Species
Human
Gene Category
Actin & Myosin Related
Domain
1-172aa
Species of Protein
Human
Manufacturer - Search Terms
MYL12B, Myosin light chain 12B regulatory, Myosin, light chain 12B regulatory, MLC-B, MRLC2, ATGP1577-10ug, ATGP1577-20ug, ATGP1577-50ug, ATGP1577-100ug, ATGP1577-250ug, ATGP1577-500ug, ATGP1577-1mg, ATGP1577-10, ATGP1577-20, ATGP1577-50, ATGP1577-100, ATGP1577-250, ATGP1577-500, ATGP1577-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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