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Recombinant human CKMT1A protein

ArtNr NKM-ATGP1590-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSHMASERR RLYPPSAEYP DLRKHNNCMA SHLTPAVYAR LCDKTTPTGW TLDQCIQTGV DNPGHPFIKT VGMVAGDEET YEVFADLFDP VIQERHNGYD PRTMKHTTDL DASKIRSGYF DERYVLSSRV RTGRSIRGLS LPPACTRAER REVERVVVDA LSGLKGDLAG RYYRLSEMTE AEQQQLIDDH FLFDKPVSPL LTAAGMARDW PD
Citations Stachowiak O., et al. (1998). Mol. Cell. Biochem. 184 (1-2): 141-51.
NCBI NP_001015001
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Creatine kinase u-type mitochondrial,Creatine kinase u-type,mitochondrial,CKMT1,CKMT1B,uMTCK
Similar products CKMT1A, mitochondrial, Creatine kinase u-type mitochondrial, Creatine kinase u-type, CKMT1; CKMT1B; uMTCK, ATGP1590-10ug, ATGP1590-20ug, ATGP1590-50ug, ATGP1590-100ug, ATGP1590-250ug, ATGP1590-500ug, ATGP1590-1mg, ATGP1590-10, ATGP1590-20, ATGP1590-50, ATGP1590-100, ATGP1590-250, ATGP1590-500, ATGP1590-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
Enzyme Activity, SDS-PAGE
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
45 kDa (403aa) confirmed by MALDI-TOF
Description
Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Recombinant human CKMT1A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol
Antigen Species
Human
Gene Category
Metabolism
Domain
40-417aa
Bioactivity Comment Only
Specific activity is > 50unit/mg, and is defined as the amount of enzyme that convert 1.0 umole of phosphate from phosphocreatine to ADP per minute at pH 7.5 at 37C.
Species of Protein
Human
Manufacturer - Search Terms
CKMT1A, Creatine kinase u-type mitochondrial, Creatine kinase u-type, mitochondrial, CKMT1; CKMT1B; uMTCK, ATGP1590-10ug, ATGP1590-20ug, ATGP1590-50ug, ATGP1590-100ug, ATGP1590-250ug, ATGP1590-500ug, ATGP1590-1mg, ATGP1590-10, ATGP1590-20, ATGP1590-50, ATGP1590-100, ATGP1590-250, ATGP1590-500, ATGP1590-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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