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Recombinant human Coagulation Factor III/Tissue Factor protein

ArtNr NKM-ATGP1683-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 4 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MSGTTNTVAA YNLTWKSTNF KTILEWEPKP VNQVYTVQIS TKSGDWKSKC FYTTDTECDL TDEIVKDVKQ TYLARVFSYP AGNVESTGSA GEPLYENSPE FTPYLETNLG QPTIQSFEQV GTKVNVTVED ERTLVRRNNT FLSLRDVFGK DLIYTLYYWK SSSSGKKTAK TNTNEFLIDV DKGENYCFSV QAVIPSRTVN RKSTDSPVEC MGQEKGEFRE <LEHHHHHH>
Citations Bogdanov V., et al. (2003) Nat. Med. 9:458-462
Mackman N., et al. (1989) Biochemistry. 28:1755-1762
NCBI NP_001984
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Tissue factor,CD142,TF,TFA
Similar products TF, Tissue Factor, CD142, Tissue factor, TFA, Coagulation Factor III, ATGP1683-10ug, ATGP1683-20ug, ATGP1683-50ug, ATGP1683-100ug, ATGP1683-250ug, ATGP1683-500ug, ATGP1683-1mg, ATGP1683-10, ATGP1683-20, ATGP1683-50, ATGP1683-100, ATGP1683-250, ATGP1683-500, ATGP1683-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
25.9 kDa (228aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description
Tissue factor, also known as F3 or CD142, is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Recombinant human F3 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Cardiovascular
Domain
33-251aa
Species of Protein
Human
Manufacturer - Search Terms
Coagulation Factor III, Tissue Factor, Tissue factor, CD142, TF, TFA, ATGP1683-10ug, ATGP1683-20ug, ATGP1683-50ug, ATGP1683-100ug, ATGP1683-250ug, ATGP1683-500ug, ATGP1683-1mg, ATGP1683-10, ATGP1683-20, ATGP1683-50, ATGP1683-100, ATGP1683-250, ATGP1683-500, ATGP1683-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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