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Recombinant human TIMP-2 protein

ArtNr NKM-ATGP1687-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMCS CSPVHPQQAF CNADVVIRAK AVSEKEVDSG NDIYGNPIKR IQYEIKQIKM FKGPEKDIEF IYTAPSSAVC GVSLDVGGKK EYLIAGKAEG DGKMHITLCD FIVPWDTLST TQKKSLNHRY QMGCECKITR CPMIPCYISS PDECLWMDWV TEKNINGHQA KFFACIKRSD GSCAWYRGAA PPKQEFLDIE DP
Citations Bahudhanapati,H., et al. (2011) J. Biol. Chem. 286 (36), 31761-31770
Seo,D.W.,et al. (2011) Peptides 32 (9), 1840-1848
NCBI NP_003246
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias TIMP metallopeptidase inhibitor 2,CSC-21K,CSC21K
Similar products TIMP2, CSC-21K, CSC21K, TIMP metallopeptidase inhibitor 2, ATGP1687-10ug, ATGP1687-20ug, ATGP1687-50ug, ATGP1687-100ug, ATGP1687-250ug, ATGP1687-500ug, ATGP1687-1mg, ATGP1687-10, ATGP1687-20, ATGP1687-50, ATGP1687-100, ATGP1687-250, ATGP1687-500, ATGP1687-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
26.1 kDa (232aa) confirmed by MALDI-TOF
Description
TIMP2 is a natural inhibitor of the matrix metalloproteinases, a group of peptidases involved in of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, this protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, TIMP2 may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular. Recombinant human TIMP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Signal Transduction
Domain
27-220aa
Species of Protein
Human
Manufacturer - Search Terms
TIMP2, TIMP metallopeptidase inhibitor 2, CSC-21K, CSC21K, ATGP1687-10ug, ATGP1687-20ug, ATGP1687-50ug, ATGP1687-100ug, ATGP1687-250ug, ATGP1687-500ug, ATGP1687-1mg, ATGP1687-10, ATGP1687-20, ATGP1687-50, ATGP1687-100, ATGP1687-250, ATGP1687-500, ATGP1687-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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