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Recombinant human alpha-Smooth Muscle Actin/ACTA2 protein

ArtNr NKM-ATGP1719-250ug
Hersteller NKMAX
Menge 250 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGSHM>EEEDS TALVCDNGSG LCKAGFAGDD APRAVFPSIV GRPRHQGVMV GMGQKDSYVG DEAQSKRGIL TLKYPIEHGI ITNWDDMEKI WHHSFYNELR VAPEEHPTLL TEAPLNPKAN REKMTQIMFE TFNVPAMYVA IQAVLSLYAS GRTTGIVLDS GDGVTHNVPI YEGYALPHAI MRLDLAGRDL TDYLMKILTE RGYSFVTTAE
Citations Sakai,H., et al. (2012) Hum. Genet. 131 (4), 591-599
Regalado,E., et al. (2011) Am. J. Med. Genet. A 155A (9), 2125-2130.
Gordon O, et al. α-actinin accounts for the bioactivity of actin preparations in inducing STAT target genes in Drosophila melanogaster. (Elife. 2018){https://pubmed.ncbi.nlm.nih.gov/30260317/}
NCBI NP_001604.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Aortic smooth muscle actin,Alpha-actin-2,Cell growth-inhibiting gene 46 protein,Actin,Aortic smooth muscle,Intermediate form,ACTSA,ACTVS,GIG46
Similar products Actin, ACTA2, ACTSA, AAT6, MYMY5, aortic smooth muscle, Actin aortic smooth muscle, ATGP1719-10ug, ATGP1719-20ug, ATGP1719-50ug, ATGP1719-100ug, ATGP1719-250ug, ATGP1719-500ug, ATGP1719-1mg, ATGP1719-10, ATGP1719-20, ATGP1719-50, ATGP1719-100, ATGP1719-250, ATGP1719-500, ATGP1719-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
44.4 kDa (400aa) confirmed by MALDI-TOF
Description
ACTA2 belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. Recombinant human ACTA2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol
Antigen Species
Human
Gene Category
Cardiovascular
Domain
3-377aa
Species of Protein
Human
Manufacturer - Search Terms
ACTA2, Actin aortic smooth muscle, Actin, aortic smooth muscle, AAT6, ACTSA, MYMY5, ATGP1719-10ug, ATGP1719-20ug, ATGP1719-50ug, ATGP1719-100ug, ATGP1719-250ug, ATGP1719-500ug, ATGP1719-1mg, ATGP1719-10, ATGP1719-20, ATGP1719-50, ATGP1719-100, ATGP1719-250, ATGP1719-500, ATGP1719-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 250 ug
Lieferbar: In stock
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