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Recombinant human ECSIT protein

ArtNr NKM-ATGP1745-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSGTCGAAL TGTSISQVPL PKDSTGAADP PQPHIVGIQS PDQQAALARH NPARPVFVEG PFSLWLRNKC VYYHILRADL LPPEEREVEE TPEEWNLYYP MQLDLEYVRS GWDNYEFDIN EVEEGPVFAM CMAGAHDQAT MAKWIQGLQE TNPTLAQIPV VFRLAGSTRE LQTSSAGLEE PPLPEDHQEE DDNLQRQQQG QS
Citations Moustakas A., et al. (2003) Genes Dev17:2855-2859
Vogel R O., et al. (2007) Genes Dev. 21: 615-624.
NCBI NP_001135937
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Evolutionarily conserved signaling intermediate in Toll pathway mitochondrial,Evolutionarily conserved signaling intermediate in Toll pathway,mitochondrial,SITPEC
Similar products ECSIT, SITPEC, mitochondrial, Evolutionarily conserved signaling intermediate in Toll pathway, Evolutionarily conserved signaling intermediate in Toll pathway mitochondrial, ATGP1745-10ug, ATGP1745-20ug, ATGP1745-50ug, ATGP1745-100ug, ATGP1745-250ug, ATGP1745-500ug, ATGP1745-1mg, ATGP1745-10, ATGP1745-20, ATGP1745-50, ATGP1745-100, ATGP1745-250, ATGP1745-500, ATGP1745-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
24.6 kDa (222aa) confirmed by MALDI-TOF
Description
ECSIT is a ubiquitously expressed protein that plays an important role as an adaptor protein in the cytosolic signal transduction cascade events triggered by Toll receptor activation. It was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF) -6 in the TLR pathway. Knockdown of ECSIT results in severely impaired complex I assembly and disturbed mitochondrial function. Recombinant human ECSIT protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Immunology
Domain
19-217aa
Species of Protein
Human
Manufacturer - Search Terms
ECSIT, Evolutionarily conserved signaling intermediate in Toll pathway mitochondrial, Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, SITPEC, ATGP1745-10ug, ATGP1745-20ug, ATGP1745-50ug, ATGP1745-100ug, ATGP1745-250ug, ATGP1745-500ug, ATGP1745-1mg, ATGP1745-10, ATGP1745-20, ATGP1745-50, ATGP1745-100, ATGP1745-250, ATGP1745-500, ATGP1745-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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