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Recombinant human AMPK beta 1/PRKAB1 protein

ArtNr NKM-ATGP1786-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGS>MGNTSSE RAALERHGGH KTPRRDSSGG TKDGDRPKIL MDSPEDADLF HSEEIKAPEK EEFLAWQHDL EVNDKAPAQA RPTVFRWTGG GKEVYLSGSF NNWSKLPLTR SHNNFVAILD LPEGEHQYKF FVDGQWTHDP SEPIVTSQLG TVNNIIQVKK TDFEVFDALM VDSQKCSDVS ELSSSPPGPY HQEPYVCKPE ERFRAPPILP
Citations Hardie D.G., et al. (2007) Nat. Rev. Mol. Cell Biol. 8:774-785
Towler M.C., et al. (2007) Circ. Res. 100:328-341
NCBI NP_006244.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 5'-AMP-activated protein kinase subunit beta-1,AMPK,HAMPKb,PRKAB1,Protein kinase AMP-activated non-catalytic subunit beta 1,AMPK subunit beta-1,AMPKb
Similar products AMPK, 5'-AMP-activated protein kinase subunit beta-1, HAMPKb, AMPK b1, ATGP1786-10ug, ATGP1786-20ug, ATGP1786-50ug, ATGP1786-100ug, ATGP1786-250ug, ATGP1786-500ug, ATGP1786-1mg, ATGP1786-10, ATGP1786-20, ATGP1786-50, ATGP1786-100, ATGP1786-250, ATGP1786-500, ATGP1786-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
32.8 kDa (293aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description
5'-AMP-activated protein kinase subunit beta-1, also known as PRKAB1, inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). Recombinant human PRKAB1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Metabolism
Domain
1-270aa
Species of Protein
Human
Manufacturer - Search Terms
AMPK b1, 5'-AMP-activated protein kinase subunit beta-1, AMPK, HAMPKb, ATGP1786-10ug, ATGP1786-20ug, ATGP1786-50ug, ATGP1786-100ug, ATGP1786-250ug, ATGP1786-500ug, ATGP1786-1mg, ATGP1786-10, ATGP1786-20, ATGP1786-50, ATGP1786-100, ATGP1786-250, ATGP1786-500, ATGP1786-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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