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Recombinant human CD46 protein

ArtNr NKM-ATGP2036-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGS>CEEPPTF EAMELIGKPK PYYEIGERVD YKCKKGYFYI PPLATHTICD RNHTWLPVSD DACYRETCPY IRDPLNGQAV PANGTYEFGY QMHFICNEGY YLIGEEILYC ELKGSVAIWS GKPPICEKVL CTPPPKIKNG KHTFSEVEVF EYLDAVTYSC DPAPGPDPFS LIGESTIYCG DNSVWSRAAP ECKVVKCRFP VVENGKQISG
Citations Riley R C., et al. (2002) Mol Reprod Dev. 62:534-546.
Iwata K., et al. (1995) J Biol Chem. 270:15148-15152.
NCBI NP_758860.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Membrane cofactor protein isoform 14,AHuS2,MCP,MIC10,TLX,TRA2.10
Similar products CD46, MCP, TLX, MIC10, TRA2.10, Membrane cofactor protein isoform 14, AHuS2, ATGP2036-10ug, ATGP2036-20ug, ATGP2036-50ug, ATGP2036-100ug, ATGP2036-250ug, ATGP2036-500ug, ATGP2036-1mg, ATGP2036-10, ATGP2036-20, ATGP2036-50, ATGP2036-100, ATGP2036-250, ATGP2036-500, ATGP2036-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
33.8 kDa (302aa) confirmed by MALDI-TOF
Description
Membrane cofactor protein isoform 14, also known as CD46, is a type I membrane protein that has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is widely distributed on thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm, but not on erythrocyte. Recombinant human CD46 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol
Antigen Species
Human
Gene Category
Immunology
Domain
35-313aa
Species of Protein
Human
Manufacturer - Search Terms
CD46, Membrane cofactor protein isoform 14, AHuS2, MCP, MIC10, TLX, TRA2.10, ATGP2036-10ug, ATGP2036-20ug, ATGP2036-50ug, ATGP2036-100ug, ATGP2036-250ug, ATGP2036-500ug, ATGP2036-1mg, ATGP2036-10, ATGP2036-20, ATGP2036-50, ATGP2036-100, ATGP2036-250, ATGP2036-500, ATGP2036-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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