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Recombinant human RFXANK protein

ArtNr NKM-ATGP2188-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 4 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGS>MELTQPA EDLIQTQQTP ASELGDPEDP GEEAADGSDT VVLSLFPCTP EPVNPEPDAS VSSPQGSSLK HSTTLTNRQR GNEVSALPAT LDCDNLVNKP DERGFTPLIW ASAFGEIETV RFLLEWGADP HILAKERESA LSLASTGGYT DIVGLLLERD VDINIYDWNG GTPLLYAVRG NHVKCVEALL ARGADLTTEA DSGYTPMDLA
Citations Krawczyk M, Masternak K, et al. (2005). Mol Cell Biol. 25(19):8607-18.
NCBI NP_604389
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias DNA-binding protein RFXANK isoform b,ANKRA1,BLS,F14150_1,RFX-B
Similar products RFXANK, ANKRA1, BLS, F14150_1, RFX-B, DNA-binding protein RFXANK isoform b, ATGP2188-10ug, ATGP2188-20ug, ATGP2188-50ug, ATGP2188-100ug, ATGP2188-250ug, ATGP2188-500ug, ATGP2188-1mg, ATGP2188-10, ATGP2188-20, ATGP2188-50, ATGP2188-100, ATGP2188-250, ATGP2188-500, ATGP2188-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
28 kDa (260aa) confirmed by MALDI-TOF
Description
RFXANK, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity. Recombinant human RFXANK protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol
Antigen Species
Human
Gene Category
Immunology
Domain
1-237aa
Species of Protein
Human
Manufacturer - Search Terms
RFXANK, DNA-binding protein RFXANK isoform b, ANKRA1, BLS, F14150_1, RFX-B, ATGP2188-10ug, ATGP2188-20ug, ATGP2188-50ug, ATGP2188-100ug, ATGP2188-250ug, ATGP2188-500ug, ATGP2188-1mg, ATGP2188-10, ATGP2188-20, ATGP2188-50, ATGP2188-100, ATGP2188-250, ATGP2188-500, ATGP2188-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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